Lecture 20: Mechanical Ventilation (Exam 3) Flashcards

1
Q

What is normal ventilation

A
  • Movement of gas in & out of the alveoli & is defined as the maintenance of norm arterial blood CO2 concentration (PaCO2) of 35-45 mmHg
  • Also should have a norm respiratory effort, rate, & rhythm
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2
Q

Label the diagram

A
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3
Q

What are the 4 different volumes & capacities the air in the lungs can be divided into

A
  • Tidal volume (Vt)
  • Inspiratory reserve vol (IRV)
  • Expiratory reserve vol (ERV)
  • Residual vol (RV)
  • Inspiratory capacity (IC)
  • Functional residual capacity (FRC)
  • Vital capacity (VC)
  • Total lung capacity (TLC)
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4
Q

What is the equation for inspiratory capacity

A

TV + IRV

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5
Q

What is the equation for functional residual capacity

A

ERV + RV

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6
Q

Equation of vital capacity

A

IRV + TV + ERV

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7
Q

Equation of total lung capacity

A

IRV + TV + ERV + RV

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8
Q

What is min ventilation (Ve)

A
  • Tidal vol (Vt) x respiratory frequency
  • mL per min
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9
Q

Answer the example

A

3,000 mL/min

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10
Q

Why do we care about ventilation

A
  • Ax drugs can alter the px ability to norm ventilate - this could lead to inadequate gas exchange, hypoventilation & eventually respiratory arrest or cardiac arrest
  • Ventilation is req for inhalant ax to be properly taken up & eliminated (controlled ventilation can maintain a smooth & stable plane of ax)
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11
Q

What are the effects of hypercapnia

A
  • Directly causes vasodilation of peripheral arterioles & myocardial depression which can cause slow heart rate, cardiac arrest, & intracranial pressure
  • Indirectly increases circulating catecholamines which can lead to cardia arrhythmias, tachycardia, increased myocardial contractility, & BP elevation
  • Narcosis @ paCO2 above 95 mmHg
  • Induces complete ax @ 245 mmHg
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12
Q

Define IPPV

A
  • Intermittent positive pressure ventilation
  • positive pressure maintained only during inspiration
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13
Q

Define IMV

A
  • Intermittent mandatory ventilation
  • Operator sets a predetermined # of positive breaths but the px can also breathe spontaneously
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14
Q

Define PEEP

A
  • Positive end-expiratory pressure
  • Airway pressure at the end of expiration is maintained above ambient pressure
  • Peep is applied when positive pressure is maintained btw/ inspirations that are delivered by a ventilator
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15
Q

What is CPAP

A
  • Continuous positive airway pressure
  • Spontaneous breathing w/ positive pressure during both inspiratory & expiratory cycles
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16
Q

Define HF(N)OT

A
  • High flow (nasal) oxygen therapy
  • Admin of warm humidified oxygen via nasal prongs using a commercially ava unit to deliver higher flow rates of O2 & an FiO2 up to 100%
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17
Q

Describe how IPPV is performed by closing/occluding the pop-off valve

A
  • close/occlude the pop off valve & squeezing the reservoir bag until 10 to 20 cm H2O is reached
  • The pop off valve is reopened so the px can passively expire
  • “manual”
  • Preferred method is to utilize the safety occlusion valve instead of actually closing the APL valve (pop off)
18
Q

Describe is IPPV is by machine (“mechanical ventilator”) convenient

A
  • B/c it frees your hands to to do other things
  • Can do harm to px if not used correctly
19
Q

What are the reasons a px may require mechanical ventilation

A
  • Simply the px has failure to oxygenate or ventilate
  • Respiratory center depression
  • Inability to adequately expand thorax
  • Cardiopulmonary arrest
  • Pulmonary edema or pulmonary insufficiency
20
Q

What are specific indications for IPPV during ax

A
  • Thoracic sx (lungs cannot be inflated when the chis is open)
  • Neuromuscular blocking drugs (If you paralyze the ocular m you paralyze the diaphragm)
  • Prolonged ax ( > 60 min)
  • Chest wall or diaphragmatic trauma ( px w/ flail chest)
  • Maintain a more stable ax plane
  • Obesity & special px positing (more like to hypoventilation or have V-Q mismatch)
  • Control of intracranial pressure
  • Convenience
21
Q

When should IPPV be started in health SA px

A

When the ETCO2 reaches the mid 50s

22
Q

What are the neg CV effects of mechanical ventilation

A
  • Neg pressure is not generated inspiration so venous return to the heart is not enhanced
  • IPPV may actually physically impede venous return to the right side of the heart (decreased stroke volume, CO, & arterial BP)
  • Exacerbated by prolonged inspiratory time, PEEP/CPAP, obstruction to exhalation, & an excessively rapid respiratory rate
23
Q

How can CV effect w/ IPPV be overcome

A

Expansion of the extracellular fluid vol & admin of inotropic drugs

24
Q

What are the other effects of IPPV

A
  • Excessive or sustained pressure can lead to over expansion & volutrauma which in return causes alveolar membrane disruption, dev of interstitial air, & eventual transfer to air to mediastinum, pleural space, or abdomen
  • Also alters neurohormonal systems like ADH release, sympathetic outflow, renin-angiotensin axis, & ANP production which can caused decreased RBF/GFR & retention w/ oliguria
25
Q

Describe a mechanical ventilator

A
  • Compliant pleated compressible bellows connected to an ax breathing circuit
  • Needs power (electricity)
  • Needs a driving force (oxygen)
26
Q

What is a double circuit ventilator

A
  • Refers to two gas sources
  • The driving gas circuit outside the bellows which compresses the bellows & the px gas circuit inside the bellows that originates in the ax machine & provides oxygen & ax gases to the px
27
Q

What are the guideline for IPPV

A
  • Vt is usually increased above norm spont Vt to compensate for pressure mediated increases in volume of the breathing system & airway
  • PIP: how much pressure is given w/ each breath
  • I to E ratio: How long in inspiration & expiration; want to spend twice as long in expiratory phase than inspiratory
  • Px w/ lung trauma, diaphragmatic hernia, or GI distention may need to have an increased respiratory rate to maintain Ve w/o creating excessive inspiratory pressures
28
Q

Fill out the chart

29
Q

Answer the example

A

Answer is C

30
Q

What are the steps of an IPPV

31
Q

What does the amount of gas delivered to the px depend on

A
  • Resistance & compliance of breathing system
  • Pxs respiratory sys
32
Q

What increases resistance? What can decrease compliance?

A
  • Increasing resistant: Obstructive dx that narrow airways; like COPD, chronic bronchitis, bronchiectasis, asthma, & emphysema
  • Decrease compliance: restrictive dx that reduce expandability; like pleural effusion, pneumothorax, morbid obesity, trauma, abdominal distension, & pulmonary fibrosis
33
Q

T/F: Although inspiratory pressure may not vary of time the Vt may changes as the compliance of the respiratory system changes

34
Q

What happens after IPPV is discont.

A
  • If PaCO2 is low spontaneous ventilation may not return b/c a certain level of PaCO2 is req to stimulate ventilation
  • Opioids, axs, neuromuscular blocking drugs, hypothermia, or hypovolemia may delay return of consciousness & therefore spontaneous ventilation
  • Px should continue to receive supllemental O2 & can be manually ventilated @ 1 to 4 bpm until spont ventilation has returned and stabilized (norm Vt & f)
35
Q

Describe volume cycled ventilators & what is the disadvantage

A
  • Inflate lungs to predetermined vol
  • Inspiratory pressure may increase if compliance decreases during ventilation
36
Q

Describe pressure cycled ventilators & what is the disadvantage

A
  • Inflate lungs to a predetermine pressure
  • Vt delivered may may decrease if respiratory compliance decreases in px
37
Q

Describe time cycled ventilators

A
  • Inflate lungs for a preset time at a predetermined gas flow rate
  • Most ax ventilators are time cycled
38
Q

Describe self inflating resuscitation sys (ambu bag)

A

Used for IPPV of small animals w/ room for supplemental O2 components

39
Q

Describe demand valve

A
  • Inserted on proximal end of endotracheal tube & delivers IPPV (O2 only)
  • Demand from a px initiated breath or from operator assistance
40
Q

What are recruitment maneuvers (RM) used for? What do they induce

A
  • Used to reinflate collapsed alveoli by applying sustained pressure above norm PIP & using PEEP to prevent derecruitment
  • Induces a temporary improvement in lung fxn in healthy dogs under general ax
41
Q

So what can you do?

A
  • Admin a “sigh” (a large pos pressure breath held for 10 to 15 sec) once every 5 mins
  • Consider adding PEEP
  • May be useful to recruit collapsed alveoli & might improve oxygenation
42
Q

Describe oxygen toxicity (Hyperoxia)

A
  • Rare but can dev w/ prolonged exposure to high O2 conc
  • Reversible in the early stages
  • Can lead to pulmonary dysfunction, pulmonary edema, & death
  • Significant species & indiv variation (recommendation is 100% O2 should not be admin for > 12 H)
  • 40 to 50% O2 is generally safe for prolonged admin but higher concentration may be needed to maintain px PaO2 @ ~ 90 to 100 mmHg