Lecture 20 Flashcards
the frontonasal prominence consists of what neural crest cells?
forebrain and midbrain
what are the four components of the pharyngeal region?
pharyngeal pouches, thyroid diverticulum, pharyngeal grooves, pharyngeal arches
neural tube gives rise to the neural ___ ___?
crest tissue
pharyngeal endoderm patterning is heavily based on exposure to what?
RA
the first pharyngeal pouch is not dependent on RA but on?
Otx2
second pouch is kind of dependent on this, and third and fourth are heavily dependent on __?
RA
this gene heavily influences the dorsoventral patterning of the pharyngeal arches?
Dlx
arch 1 ectoderm uses this gene to single migrating neural crest cells and influence development of arch 1?
Edn-1
frontonasal ectoderm zone is induced by this gene from the forebrain?
Shh
what two processes make up the primordia for jaws?
maxillary and mandibular
this is a slender, elongated cartilaginous rod that develops within the first arch. the mandible forms around it and it contains two derivatives, articular and quadrate.
meckel’s cartilage
this is a synovial joint with an articular disk, and the formation involves the early expression of Barx-1.
temporomandibular joint
quadrate bone moves into the middle ear and becomes the
incus
articular bone moves into the middle ear and becomes the
malleus
this part of the nose requires Pax6 and retinoids and develops from the anterolateral edges of neural plate
nasal placodes
this part of the nose is an invagination of nasal placodes and is a source of retinoids that stimulate FGF-8, also they deepen to form choanae
nasal pits
this part of the nose is derived from the dorsal epithelium of nasal pits and requires FGF-8
olfactory epithelium
what are the 5 stages of tooth development? which stage contains the enamel organ and dental papilla?
dental lamina, tooth bud, cap stage, bell stage, dental sac. bell stage.
the enamel organ gives rise to the
ameloblasts
the dental papilla gives rise to the
odontoblasts
this stage is C shaped bands or oral ectoderm
dental lamina
this stage marks the position of a single tooth
tooth bud
this stage in an inverted cup shaped layer of ectoderm
cap stage
this stage is cone shaped primordium organ contains enamel organ and dental papilla
bell stage
this stage will form a periodontal ligament
dental sac
branching pattern of salivary glands depends heavily on what gene
Shh
for salivary gland development, the signaling between what two genes occurs between within the epithelium
Shh and FGF