Lecture 2 Urinary System Embryology Flashcards
What part of the mesoderm goes on to form the kidney and reproductive system
Intermediate plate mesoderm
What is the allantois
Outpouching of endoderm at the handout that extends into the body stalk
What is the cloaca
Single posterior opening for a birds digestive, urinary and reproductive tracts
What eventually happens to the cloaca
Divides to form rectum and urogenital sinus
What does the urogenital sinus eventually become
Urinary bladder and the caudal end forms the urethra
What is the fate of the allantois
Obliterates to form the urachus
In week 4 the intermediate mesoderm becomes___
Pronephros
What is the pronephros
Rudimentary tubules
Pronephric duct
Where does the pronephric duct drain into
Cloaca
During week 5 what happens to the pronephros
Degenerates leaving the pronephric duct
What does the pronephric duct become
Mesonephric duct
What structure functions as the kidney for 4 weeks
Mesonephris
When does the metanephros start to develop
Week 5
When does the metanephros start to function
Week 9
What is the metanephros
Uteric bud
and develops off the mesospheric duct and metanephric mesoderm
The uteric bud goes on to develop into
Renal pelvis, ureter, collecting duct and calyces
What happens to the mesonephros
Incorporated into the developing gonad and undifferentiated cells from the yolk sac migrate in to form the spermatogonia/oogonia
What do the mesonephric tubules become
Rate testis
What does the mesonephric duct become
Vas deferens- male
Ovary- females
The first 4 generations of branches of the uteric bud become
major calyces
The second 4 generations of branches of the uteric bud become
minor calyces
The remaining generations of the branches of the steric bud become
Collecting tubules
Where does the nephron develop from
Metanephric mesoderm
Collecting duct, calyces, pelvis and ureter develop from
The uteric bud
Describe the ascent of the kidneys
- Initially lie on either side of the bladder and in the developing pelvis
- Appears the ascend into abdomen due to differential growth of the lower body, inferiorly away from kidneys
- Kidneys come to lie in upper abdomen (T12-L3)
- Hilum rotates from ventral to medial
- Ascend stops when they come into contact with adrenal glands
- Segmental breakdown and reform of vascular supply during ascent
Name anomalies in the development of the kidneys
- Multiple ureters
- Abnormal sites at which ureter may open
- Congenital polycystic kidney
- Aberrant renal arteries
- Lobulated kidney
- Horseshoe kidney
- Pancake kidney
