Lecture 2: Red Eye Flashcards
How does bacterial conjuctivitis typically present?
Copious PURULENT discharge.
What are the MC organisms for bacterial conjunctivitis?
S. Aureus (MC for adults)
Strep pneumo (MC for children, followed by mcat and hflu)
Pseudomonas (Contact wearers)
How is bacterial conjunctivitis treated?
- Mild-moderate: Topical sulfonamide like polymixin B/trimethoprim.
- Severe OR pseudomonas: Moxifloxacin, Oculfox/floxin, cipro
How is genital bacterial conjunctivitis treated?
- Gonococcal: rocephin IM. (corneal involvement = ER)
- Chlamydial: Azithromycin PO.
How does gonococcal conjunctivitis present?
rip
What is trachoma? What causes it?
Chlamydial infection of the eye. It is the MC infectious cause of blindness.
How does viral conjunctivitis typically present?
Copious WATERY discharge.
Google says it is actually rarely bilateral, and her table on slide 18 also says that as well.
What is the MCC of viral conjunctivitis? What environment?
Adenovirus, usually swimming pools.
What condition is viral conjuctivitis associated with?
Preauricular adenopathy.
How is viral conjuctivitis treated?
Supportive care and cold compresses.
How does allergic conjunctivitis typically present?
Stringy discharge with cobblestone papillae on exam.
Hyperemia and chemosis
How is allergic conjunctivitis treated?
- Mild-moderate: topical antihistamines, such as ketotifen or olopatadine. Can also use NSAIDs, mast cell stabilizers, or oral antihistamines.
- Severe: topical corticosteroids UNLESS h/o of suspected HSV.
What is the uvea made of?
Anterior uvea: iris/pupil and ciliary body
Posterior uvea: Choroid
What is the MC type of uveitis?
Acute nongranulomatous anterior uveitis
How does ANTERIOR non-granulomatous uveitis usually present?
Unilateral pain with acute presentation.
* Redness
* Photophobia
* Visual loss
How does ANTERIOR granulomatous uveitis present?
- Indolent
- Blurred vision
- Mildly inflamed
- Recurrent
What is the MC of anterior non-granulomatous uveitis?
Immunologic, usually HLA-B27 conditions.
* Anklyosing spondylitis
* Reactive arthritis
* psoriasis
* ulcerative colitis
* crohn’s
What usually causes granulamatous anterior uveitis?
- Sarcoidosis
- Toxoplasmosis
- TB
- Syphilis (salt and pepper fundus)
- Herpes
- Ocular trauma
How is anterior uveitis/iritis diagnosed?
Slit-lamp examination
What specific findings do you find in iritis?
Granulomatous: Large keratic precipitates.
Non-granulomatous: small keratic precipitates.
What is a hypopyon?
Collection of inflamed epithelial cells.
Looks like pus in the anterior chamber of the eye.
What exam findings would I expect in posterior uveitis?
New lesions: yellow with indistinct margins, retinal hemorrhages.
Old lesions: definite margins, commonly pigmented.
What kind of symptoms would I expect in posterior uveitis?
Gradual vision loss
Floaters
Bilateral usually.
What are the MCC of posterior uveitis?
Same as anterior + pars plantis or autoimmune retinal vasculitis.
How is anterior uveitis treated?
Referral.
Topical corticosteroids #1 + pupil dilation!
How is posterior uveitis treated?
Referral.
Special corticosteroid therapy.
What is the predominant cell in non-granulomatous anterior uveitis?
PMN cells.
What is the MC cell type in granulomatous anterior uveitis?
Macrophages and histiocytes
What is keratitis? 4 causes?
Inflammation of the cornea.
* Bacterial
* Viral (HSV, HZV)
* Acanthamoeba (parasite)
* Fungal
What is the biggest risk factor for keratitis?
Contact lens wear overnight.
What is the MC pathogen to cause bacterial keratitis?
Pseudomonas
How does bacterial keratitis typically present?
- Hazy cornea
- Hypopyon
- Stromal abscess
- Patients typically complain of a foreign body sensation and trouble keeping their eye open.
How is bacterial keratitis treated?
- Emergent referral
- Fluoroquinolone empiric tx.
- Tailor treatment once culture back.
How does HSV keratitis typically present?
- Red eye
- Photophobia
- Foreign body sensation
- Watery discharge
- Dendritic lesions on fluoroscein stain
How is HSV keratitis treated?
- Urgent referral
- Topical/oral antivirals
- Valacyclovir often used to prevent recurrence.