Lecture 2 Integument & Glands Flashcards
What are glands and what is their function?
- Down growth of epithelium that can be multicellular or unicellular
- specialized to produce and secrete substances that work on specific organs or tissues in the body
What are exocrine glands?
- Glands that secrete product directly onto a surface or into a duct
- classified by shape, product, and mechanism of secretion
What are endocrine glands?
secrete product into connective tissue or bloodstream
What are the types of products of exocrine glands?
Serous
- proteinaceous, watery, usually stains darkly
Mucous
-viscous, water-heavy, usually stains light
What are the mechanisms of secretion?
Merocrine (eccrine)
- vesicles of product released from cell
Apocrine
-vesicles coated in lipid membrane before release
Holocrine
-product builds in cytoplasm, cell dies and releases product and cellular debris
How are exocrine classified?
(Simple or compound duct) + (shape of secretory protein) + (serous or mucous product)
What are the different types of simple exocrine glands?
- Simple Tubular
- Simple Coiled Tubular
- Simple Acinar
- Simple Branched Acinar
What are the different types of compound exocrine glands?
- Compound Acinar
- Compound Tubular
- Compound Tubuloacinar
What are the functions of the skin?
Protection
- Trauma- heals quickly - Infection- physical and chemical barrier - Dehydration/ overhydration- prevents excess loss or absorption of water
Sensation
-several types of nerve endings react to temperature, pressure, vibrations, texture, and injury
Thermoregulation
-monitors the temperature of the body surface, and reacts to maintain appropriate response
Vitamin D
-initiates the synthesis of vitamin D
Communication
What are the general layers of the Integument and what are they made of ?
Epidermis
-stratified squamous keratinized epithelium
Dermis
- dense irregular CT - blood vessels, nerves, glands, and hair follicles
Hypodermis
-adipose tissue
What are the layers of the epidermis?
Stratum corneum -stratum lucidem Stratum granulosum Stratum spinosum Stratum Basale
What are characteristics of thick skin?
- They are found at the palms of hands and soles of feet
- eccrine sweat glands
- have a thicker stratum corneum
What are characteristics of thin skin?
everywhere except palms and soles
- has hair
- has sebaceous glands
- has eccrine sweat glands
- has thinner stratum corneum
What cells are found in the epidermis?
Keratinocytes
Melanocytes
Langerhans Cells
Merkel Cell
What is the predominant cell type in the epidermis?
Keratinocytes and they synthesize keratin
What cells secretes melanin?
melanocytes
Where are Langerhans cells found?
part of the immune system
What are merkel cells?
Sensory cells
What does eumelanin stain under a microscope?
brownish black
What does Phomelanin stain?
reddish yellow
What are color and intensity of pigmentation dependent on?
Dependent on type and distribution of melanin