Lecture 2 - Conditions of Female Reproductive System Flashcards

1
Q

what are the two main cycles involved in the female reproductive cycle?

A

ovarian cycle and menstrual cycle

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2
Q

what changes occur in the ovarian cycle?

A

changes in the ovary during and after maturation of the oocyte

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3
Q

what does the menstrual cycle involve changes in?

A

changes in the endometrium to prepare the uterus to receive a fertilized ovum

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4
Q

what occurs during the menstrual cycle if implantation does not occur?

A

the stratum functionalis is shed during menstruation

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5
Q

what hormones are secreted by the corpus luteum?

A

progesterone, estrogen, relaxin and inhibin

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6
Q

what hormones are secreted by the ovarian follicles?

A

estrogen and inhibin

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7
Q

what hormone is released by the hypothalamus?

A

GnRH

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8
Q

what does GnRH stimulate the release of from the anterior pituitary gland?

A

FSH and LH

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9
Q

what 2 processes does the FSH stimulate?

A

initial development of ovarian follicles and further development of the ovarian follicles and their secretion of estrogen and inhibin

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10
Q

what 2 structures does FSH stimulate?

A

growing follicles and ovaries

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11
Q

what 2 processes does the LH stimulate?

A

ovulation (secretion of estrogen and inhibin) and the secretion of the progesterone, estrogen, relaxin and inhibin by the corpus luteum

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12
Q

at what points of the reproductive cycle are the FSH, estrogen, LH and progesterone at their highest?

A

FSH - fairly constant
estrogen - pre ovulation
LH - at ovulation
progesterone - post ovulation

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13
Q

what are 5 of the most common symptoms of perimenopause?

A
  1. irregularity/skipped menstrual cycle
  2. sleep disturbances/fatigue
  3. increased body temp
  4. mood changes (anxiety/depression)
  5. difficulty concentrating
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14
Q

what is the general definition of menopause?

A

complete cessation of ovarian function and menses for 12 consecutive months

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15
Q

what is the typical age of onset of menopause?

A

45-50 years old

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16
Q

what happens to the hormones and ovarian follicles upon menopause?

A

estrogen and progesterone decline; number of ovarian follicles approaches zero

17
Q

what could bleeding after the onset of menopause indicate?

A

possible cancer or polyps

18
Q

premenopausal women who have a hysterectomy will experience___menopause

19
Q

what is the general definition of premature menopause?

A

cessation of menstruation before age of 40 years old - premature ovarian failure

20
Q

what can be the cause of panic attacks, depression and mood swings in menopause?

A

decreased serotonin levels

21
Q

what is a hysterectomy?

A

surgical removal of the uterus

22
Q

what are 4 indications for a hysterectomy?

A

endometriosis, ovarian cyst, excessive bleeding, and cancer of cervix, uterus or ovaries

23
Q

what is endometriosis?

A

appearance of endometrial tissue outside the uterus causing pelvic pain

24
Q

what are 2 types of hysterctomy?

A

complete - removal of cervix

radical - removal of uterus, tubes, ovaries, part of vagina, pelvic lymph nodes and supporting ligaments

25
what are 5 indications for hormone replacement therapy?
1. hot flashes 2. vaginal dryness 3. prevention of osteoporosis 4. decreased risk of colon cancer and stroke 5. improves pain tolerance and serotonin levels
26
what are 5 increased risks with HRT?
1. MI or stroke (blood clots in general) in first year (healthy women) 2. endometrial cancer 3. breast cancer with prolonged use > 4years 4. gallstones 5. increased breast density leading to lower sensitivity of mammograms
27
what are 5 precautions/contra indications of HRT?
1. hx of blood clots, strokes or TIA 2. pancreatic or liver disease 3. migraines 4. uterine fibroids/endometriosis 5. benign brest disease or breast/endometrial cancers