lecture 2 Flashcards
what is epithilia
sheets of contiguous cells, varied in embryonic origin that cover the external surface of the body and line internal surfaces
position of basement membrane
thin, flexible, acellular layer between epithelial cells and connective tissue
function of basement membrane
strong layer where epithilial cells adhere. cellular and molecular filter
structure of basement membrane
made of basal lamina, closest to epithilial cells. may also have reticular fibrils from connective tissue which makes it thicker
what does simple mean
one cell layer thick
how does simple squamous cells look
very flat with bulging nucleus
what does simple squamous line
blood vessels: endothelium body cavities; pericardium, pleural sac, peritoneum: mesothelium alveoli bowmans capsule loop of henle inner and middle ear
VACKE
functions of simple squamous
lubrication in body cavities gas exchange in alveoli barrier in bowmens active transport in meso and endothelium BAGL
where is simple cuboidal
thyroid follicles, ducts of exocrine glands, kidney tubules, ovary
KOTE
functions of simple cuboidal
exocrine gland absorption and conduit kidney tubules: absorption and secretion Ovary: barrier Thyroid: hormone synthesis, storage and metab HAB
where is simple columnar epithilia
stomach, small intestine, gall bladder, uterus, oviduct, testis, larger ducts
stomach and repro
functions of simple columnar
absorption: small intestine and colon and gall bladder
secretion: stomach, small intestine, colon
lubrication; small intestine and colon
transport; oviduct
LAST
function of microvilli
microvili is for absorption
in simple columnar, microvili occludin binds adjacent p membranes together in the apical (lumen) epithilia. membrane proteins cant pass through zona occludens. cell can restrict proteins to apical or basal side.
pseudo stratified epithilia location
nasal cavity, trachea, bronchi (upper respiratory)
epididymis
pseudo stratified epithilia function
secretion
absorption- epididymis
mucus secretion- urt
Stratified Squamous Non-Keratinised Epithelia location
Locations include:
- Oral cavity
- Oesophagus
- Larynx
- Vagina
- Part of anal canal
- Surface of cornea
- Inner surface of eyelid
Stratified Squamous Non-Keratinised Epithelia function
Functions include:
- Protection against abrasion (all sites)
- Reduces water loss whilst remaining moist
Stratified Squamous Keratinised Epithelia
Locations
- Surface of skin
- Limited distribution in oral cavity
Stratified Squamous Keratinised Epithelia functions
Functions include:
- Protection against abrasion and physical trauma
- Prevents water loss
- Prevents ingress of microbes
- Shields against UV light damage
Stratified Transitional (urinary) Epithelia Locations
include:
- Renal calyces (singular = calyx)
- Ureters
- Bladder
- Urethra
Stratified Transitional (urinary) Epithelia function
Functions include:
- Distensibility
- Protection of underlying tissue from toxic chemicals
renewal rate depends on
function, location, and constant rate for each epithilium (unless injury which accelerates)
renewal rate for epidermis
28 days
small intestine renewal rate
4-6 days
what happens is cells arent renewed
proliferation triggers replacement cells