lecture 2 Flashcards
What is a Paradigm
- …a set of basic assumptions, a general perspective, that
defines how to: - conceptualize and study a subject
- gather and interpret relevant data
- think about a particular subject
- A paradigm is a framework, or perspective, that shapes
the way we think about problems in the world (in our
case, human behaviour).
Paradigms in the Study of Mental
Disorders
- Biological Paradigm
- Cognitive-Behavioural Paradigm
-Behavioural perspective - Cognitive perspective
- Psychoanalytic paradigm
- Humanistic Paradigm
- Integrative Paradigms
- Diathesis–stress
- Biopsychosocial
Etiology
the cause or origin of a disease
Symptomatology
the study of, or the treatment of, the
symptoms of a disease
Biological Paradigm
Mental disorders caused by aberrant or
defective biological processes
what does the biological paradigm focus on
Focuses on
* Genetic Heritability
* Neurochemical Communication
* Brain Structure
Focus on interaction between organic functioning
(genetics, physiological & neurological systems) and
behaviour (normal & abnormal).
Genotype
unobservable genetic constitution
* The total genetic makeup of an individual
* Fixed at birth, but it should not be viewed as a static entity
Phenotype
totality of observable, behavioural
characteristics
* Dynamic (i.e., it changes over time)
* Product of an interaction between genotype and environment
Family method
Can be used to study a genetic
predisposition among members of a
family b/c the average number of
genes shared by two blood relatives is
known
* Index cases, or probands
* Individuals who bear the diagnosis in
question.
Twin method
- Concordance rates
- When the MZ concordance rate is higher
than the DZ rate, the characteristic being
studied is said to be heritable.
adoptees method
In the adoptees’ study method, researchers identify proband birth parents with a certain characteristic (e.g., alcoholism) and then examine the outcome of these probands’ adopted-away children.
Molecular genetic studies identify:
which genes are involved
in behavioural disorders
Linkage analysis
uses genetic markers as a clue in locating
genes controlling disorders
Genetic Marker
a gene for which we know the location and
function.
* Genes have a tendency to be passed along in clusters, so if we can
find some characteristic that is generally inherited along with the
disorder (and if we know the gene location for that characteristic),
then we can look at nearby genes to find a gene for the disorder.10
Molecular Genetics: Method
Frontotemporal Dementia (FTD):
The second most common type of dementia other
than Alzheimer’s disease
Epigenetics
heritable changes in gene activity that are
caused by environmental experience
Dias & Ressler (2014)
- Examined an inherited fear response
- Trained male mice to fear the smell of acetophenone (a chemical scent comparable to cherries or almonds) by
exposing them to the smell while being given a series of electric shocks - The mice eventually gave a fear response (shuddering) to the smell
-The mice were then bred, and the offspring were tested
with the smell (descendants had no contact with male
parent)
Each neuron has four major parts:
- (1) the cell body
- (2) several dendrites
- (3) one or more axons of varying lengths
- (4) terminal buttons
Nerve impulse
A change in the electric potential of the cell that
travels down the axon to the terminal endings
Synapse and neurotransmitters
Chemical substances that allow a nerve impulse
to cross the synapse.
Mental Disorder in regards to synapse
Imbalance in levels of
one or more
neurotransmitters
* Receptors are the issue