lecture 19 Flashcards

1
Q

Describe the major functions of the digestive system.

A

o Ingestion: The process of taking in food through the mouth.
o Mechanical breakdown: The physical breakdown of food into smaller pieces, such as chewing and churning in the stomach.
o Propulsion: Moving food along the digestive tract, including swallowing and the peristaltic movement of food down the esophagus and intestines.
o Chemical Digestion: The breakdown of food into simpler molecules by enzymes and acids, which allows nutrients to be absorbed.
o Absorption: The process by which nutrients, water, and minerals are absorbed into the bloodstream from the digestive tract, particularly in the small intestine.
o Defecation: The elimination of indigestible substances and waste products from the body as feces.

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2
Q

Explain the differences between the gastrointestinal (GI) tract (alimentary canal) and the accessory digestive organs.

A

Gastrointestinal (GI) Tract (Alimentary Canal):
 Includes the mouth, esophagus, stomach, small intestine, large intestine, rectum, and anus.
 It is the continuous tube through which food travels and is digested.
 The primary function is to process and absorb nutrients from food.
Accessory Digestive Organs:
 Include the salivary glands, liver, pancreas, and gallbladder.
 These organs are not part of the GI tract but contribute essential fluids and enzymes to aid digestion.
 The salivary glands secrete saliva to begin the breakdown of carbohydrates, the liver produces bile to emulsify fats, the pancreas secretes digestive enzymes and bicarbonate to neutralize stomach acid, and the gallbladder stores and concentrates bile.

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3
Q

Compare and contrast mechanical digestion and chemical digestion, including where they occur in the digestive system.

A

Mechanical Digestion:
o Involves the physical breakdown of food into smaller pieces.
o Occurs primarily in the mouth (through chewing) and the stomach (through churning).
o It does not change the chemical structure of food but increases surface area for chemical digestion.
Chemical Digestion:
o Involves the breakdown of food into simpler molecules by digestive enzymes and acids.
o Begins in the mouth with enzymes like amylase breaking down carbohydrates, continues in the stomach with the action of pepsin on proteins, and completes in the small intestine with enzymes from the pancreas and bile from the liver.
o Chemical digestion allows for the absorption of nutrients (like sugars, amino acids, and fatty acids) into the bloodstream.

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4
Q

Both mechanical and chemical digestion work together to

A

Both mechanical and chemical digestion work together to break down food for nutrient absorption. Mechanical digestion physically prepares the food, while chemical digestion breaks it down into molecular forms that the body can absorb.

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5
Q

Trace the pathway of ingested substances through the gastrointestinal (GI) tract.

A

o Mouth: Food is ingested and mechanically broken down by chewing. Saliva, which contains the enzyme amylase, begins chemical digestion, especially carbohydrates.
o Esophagus: After swallowing, food moves down the esophagus by peristalsis (wave-like muscle contractions) to reach the stomach.
o Stomach: The stomach further churns food and secretes gastric juices containing hydrochloric acid and pepsin, initiating the digestion of proteins. The food is turned into a semi-liquid substance called chyme.
o Small Intestine: The chyme enters the small intestine, where most of the digestion and nutrient absorption occurs. Enzymes from the pancreas break down fats, proteins, and carbohydrates. The liver secretes bile to emulsify fats.
o Large Intestine: Water and electrolytes are absorbed in the large intestine, and indigestible materials are prepared for excretion. Beneficial bacteria also help break down certain substances.
o Rectum and Anus: Finally, the indigestible remains are stored in the rectum and expelled from the body through the anus during defecation.

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6
Q

identify the lips

A

o Lips: Serve as the opening for the mouth. They help in the manipulation of food and speech formation.

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7
Q

hard palate

A

o Hard Palate: The bony part of the roof of the mouth. It provides a rigid surface for the tongue to push food against during chewing.

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8
Q

soft palate

A

o Soft Palate: The muscular portion at the back of the roof of the mouth. It rises to close off the nasal passages during swallowing to prevent food from entering the nasal cavity.

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9
Q

uvula

A

o Uvula: The small, fleshy projection hanging from the soft palate. It helps with speech and helps in preventing food from entering the nasopharynx during swallowing.

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10
Q

frenula

A

o Frenula (Plural: Frenulum): Small folds of mucous membrane that help anchor the tongue to the floor of the mouth (lingual frenulum) and the lips to the gums (labial frenulum).

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11
Q

gingivae

A

o Gingivae (Gums): The soft tissue surrounding the teeth, providing protection and support for the teeth.

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12
Q

tongue

A

o Tongue: A muscular organ responsible for moving food around the mouth during chewing, aiding in swallowing, and assisting in speech. It is also involved in the sensation of taste through taste buds located on its surface

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13
Q

Describe and order the layers of a general tooth.

A

o Enamel: The outermost layer, made of a hard, mineralized substance primarily composed of hydroxyapatite. Enamel is the hardest substance in the human body and protects the tooth from physical and chemical damage.
o Dentin: The layer beneath the enamel, made of a hard, bone-like material. Dentin is less mineralized than enamel but still provides structure and support for the tooth. It contains microscopic tubules that transmit sensations (such as pain).
o Pulp: The innermost part of the tooth, consisting of soft tissue that contains blood vessels, nerves, and connective tissue. The pulp provides nutrients to the tooth and is responsible for sensation (pain).

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14
Q

incisors

A

o Incisors (8 total): Located at the front of the mouth, they are flat and sharp, used for cutting food.

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15
Q

canines

A

o Canines (4 total): Pointed teeth located next to the incisors. They are used for tearing food.

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16
Q

premolars

A

o Premolars (8 total): Located behind the canines, premolars have flat surfaces with ridges and are used for crushing and grinding food.

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17
Q

molars

A

o Molars (12 total, including wisdom teeth): Located at the back of the mouth, these teeth have large, flat surfaces and are used for grinding food. Molars include the third molars, or wisdom teeth, which may or may not be present in some individuals.

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18
Q

the three major salivary glands

A

parotid
submandibular
sublingual

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19
Q

Describe the structure and function of the salivary glands.

A

o Parotid Glands: Located near the ears, these are the largest salivary glands. They primarily secrete a serous, watery saliva rich in enzymes, especially amylase, which begins the digestion of carbohydrates.
o Submandibular Glands: Located beneath the jaw, these glands produce both serous and mucous saliva. They secrete saliva that helps with both the initial digestion and lubrication of food.
o Sublingual Glands: Located under the tongue, these glands primarily produce mucous saliva, which aids in lubricating the mouth and forming a food bolus for easier swallowing.

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20
Q

composition of saliva

A

o Water: Makes up most of saliva and helps with moistening and lubricating food.
o Electrolytes: Sodium, potassium, calcium, and bicarbonate ions help maintain the pH of the mouth and neutralize acids.
Enzymes:
o Amylase: Begins the breakdown of starches into sugars.
o Lingual Lipase: Begins the digestion of fats, especially in the stomach.
o Mucins: Glycoproteins that help lubricate and protect the mucous membranes in the mouth and the digestive tract.
o Lysozyme: An antibacterial enzyme that helps control bacterial growth in the mouth.
o Immunoglobulins (IgA): Help protect against infections by binding to pathogens and preventing their attachment to tissues.

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21
Q

functions of saliva

A

o Lubrication: Facilitates the movement of food in the mouth and aids in swallowing.
o Digestion: The breakdown of carbohydrates begins through the action of amylase.
o Protection: Helps protect the teeth and mouth from harmful bacteria and acids by washing away food particles and neutralizing acids.
o Taste: Moistens food, allowing taste buds to function properly.
o Buffering: Helps maintain oral pH and prevent tooth decay by neutralizing acids.

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22
Q

functions of the salivary glands

A

The salivary glands produce and secrete saliva, which moistens and lubricates food, making it easier to chew and swallow. Saliva also contains enzymes like amylase to begin the breakdown of carbohydrates, and lysozyme, an enzyme that has antibacterial properties, helping protect against infections.

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23
Q

anatomy of the nasopharynx

A

 Location: The uppermost part of the pharynx, located behind the nasal cavity.
 Passage of Air: The nasopharynx serves as the passageway for air from the nasal cavity to the larynx. It also connects to the middle ear via the Eustachian tubes.
 Passage of Food: The nasopharynx does not normally allow food to pass through it since food is directed into the oropharynx during swallowing.

24
Q

anatomy of the oropharynx

A

 Location: The middle portion of the pharynx, located behind the oral cavity.
 Passage of Air: The oropharynx allows the passage of air from the nasopharynx to the larynx.
 Passage of Food: The oropharynx is the primary area for the passage of food and liquids from the mouth to the esophagus during swallowing. It is where food is directed when you swallow.

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laryngopharynx (hypopharynx)
 Location: The lowest part of the pharynx, located behind the larynx and extending to the esophagus.  Passage of Air: The laryngopharynx allows air to pass from the oropharynx to the larynx, which leads to the trachea and lungs.  Passage of Food: Food and liquids are directed into the esophagus during swallowing from the laryngopharynx.
26
define deglutition
Deglutition is the process of swallowing, which involves the coordinated movement of various structures to move food and liquids from the mouth to the esophagus. The process can be divided into three phases:
27
oral phase of deglutition
Oral Phase (Voluntary Phase):  Structures Involved: Tongue, soft palate, teeth, and lips.  Process: Food is chewed and mixed with saliva to form a bolus. The tongue pushes the bolus to the back of the mouth and into the oropharynx, beginning the process of swallowing.  Pharyngeal Phase (Involuntary Phase):  Structures Involved: Pharynx, soft palate, uvula, epiglottis, and larynx.
28
the process the oral phase of deglutition
 Once the bolus reaches the oropharynx, the soft palate rises to close off the nasopharynx to prevent food from entering the nasal cavity.  The uvula also rises to ensure that food does not enter the nasopharynx.  The epiglottis moves downward to cover the glottis (the opening to the trachea), preventing food from entering the airway.  The larynx moves upward and forward to help close the trachea.  Muscles of the pharynx contract in a coordinated manner to propel the bolus into the laryngopharynx and towards the esophagus.
29
esophageal phase of deglutition
Esophageal Phase (Involuntary Phase):  Structures Involved: Esophagus, lower esophageal sphincter.  Process: The bolus enters the esophagus, and peristalsis (a wave-like contraction of the esophageal muscles) pushes the bolus down the esophagus. The lower esophageal sphincter (LES) relaxes to allow the bolus to enter the stomach.
30
Changes in Position of the Glottis and Larynx to Prevent Aspiration
During deglutition, the body takes steps to prevent aspiration, which is when food or liquid enters the airway (trachea) instead of the esophagus. These protective actions are critical to avoid choking and respiratory complications:
31
closure of the glottis
As the bolus moves through the pharynx, the epiglottis covers the glottis (the opening to the trachea), effectively sealing off the airway. This prevents food or liquids from entering the respiratory tract.
32
raising of the larynx
The larynx moves upward and forward during swallowing, which helps to tighten the airway and ensure that the glottis is fully covered by the epiglottis. This action further protects the trachea from food or liquid entering the airway.
33
the esophagus
The esophagus is a muscular tube that connects the pharynx (throat) to the stomach. It is approximately 25 cm (10 inches) long in adults. The esophagus runs behind the trachea (windpipe) and heart and in front of the vertebral column. It passes through the diaphragm at the esophageal hiatus to enter the abdominal cavity, where it connects to the stomach at the cardiac orifice.
34
the regions of the esophagus
 Cervical region: The esophagus begins in the neck, posterior to the trachea, and runs along the vertebral column.  Thoracic region: It passes through the thoracic cavity, between the trachea and the spine. The heart lies anteriorly, and the descending aorta runs posteriorly.  Abdominal region: After passing through the diaphragm, it enters the stomach at the cardia.
35
Describe the general functions of the esophagus.
o Swallowing (Deglutition): The esophagus aids in the swallowing process, pushing food from the oropharynx to the stomach. o Prevention of gastric reflux: The lower esophageal sphincter (LES) prevents the backflow of stomach contents into the esophagus, protecting it from damage.
36
Describe the anatomic specializations of the esophageal tunics (e.g., composition of the mucosa and muscularis [muscularis externa]) compared to the tunics of the rest of the GI tract.
o Mucosa: The mucosa of the esophagus is stratified squamous epithelium, which is designed to withstand mechanical abrasion from food. This contrasts with the simple columnar epithelium seen in the stomach and intestines, which is specialized for secretion and absorption.  The mucosa also has a lamina propria (a layer of connective tissue) and a muscularis mucosa (a thin layer of smooth muscle). o Submucosa: The submucosa contains blood vessels, lymphatics, and esophageal glands, which secrete mucus to lubricate the esophagus, facilitating the passage of food. o Muscularis externa: The muscularis externa has both skeletal muscle (in the upper part of the esophagus) for voluntary control of swallowing and smooth muscle (in the lower part) for involuntary peristalsis.  The smooth muscle is organized into two layers: an inner circular layer and an outer longitudinal layer. The upper third is mostly skeletal muscle, the middle third has a mixture of skeletal and smooth muscle, and the lower third is entirely smooth muscle. o Adventitia (or serosa in the abdominal portion): The esophagus in the thoracic region has an adventitia, a connective tissue covering. In the abdominal region, it has a serosa, which is a layer of mesothelium (a type of simple squamous epithelium) covered by a thin layer of connective tissue.
37
define peristalsis
o Peristalsis is a series of wave-like muscular contractions that move food along the digestive tract. In the esophagus, peristalsis occurs as a coordinated contraction of the smooth muscle in the muscularis externa, which pushes food from the mouth toward the stomach. This process is initiated voluntarily during swallowing but continues involuntarily once food is in the esophagus. It ensures that food is moved efficiently down the esophagus.
38
Relate the anatomic specializations of the esophagus to the organ’s functions.
o Stratified squamous epithelium in the mucosa protects the esophagus from mechanical damage as food is swallowed. o Esophageal glands in the submucosa secrete mucus that lubricates the esophageal lining, facilitating smooth passage of food and preventing damage from friction. o The muscularis externa with both skeletal and smooth muscle allows for the voluntary control of swallowing in the upper esophagus and involuntary peristalsis in the lower esophagus. o The lower esophageal sphincter (LES), made of smooth muscle, prevents reflux of stomach contents into the esophagus, which is essential for preventing acid damage to the esophageal lining.
39
The gastrointestinal (GI) tract, or digestive tract, is a continuous pathway for food processing, starting with the mouth, moving through the esophagus, stomach, small intestine, large intestine, and ending at the anus.
Here's a more detailed breakdown: Mouth: Where food intake and initial breakdown begin. Esophagus: A muscular tube that propels food from the mouth to the stomach. Stomach: A muscular organ that stores food and mixes it with digestive juices. Small Intestine: The primary site for nutrient absorption, with three sections: duodenum, jejunum, and ileum. Large Intestine: Absorbs water and electrolytes, and forms and stores feces. Anus: The opening through which waste is eliminated
40
The GI tract has four layers:
mucosa (epithelium, lamina propria, muscularis mucosae), submucosa, muscularis externa (inner circular and outer longitudinal muscle layers), and serosa (or adventitia). structure
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1. Mucosa:
Gross Anatomy: The innermost layer, facing the lumen of the GI tract. Microscopic Structure: Consists of: Epithelium: Varies depending on the location (e.g., stratified squamous in the esophagus, simple columnar in the stomach and intestines).
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lamina propria
Lamina Propria: Loose connective tissue containing blood vessels, lymphatic tissue, and nerves.
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muscularis mucosae
Muscularis Mucosae: A thin layer of smooth muscle that separates the lamina propria from the submucosa. Function: Protection, absorption, and secretion (e.g., mucus, enzymes, hormones).
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submucosa
2. Submucosa: Gross Anatomy: A layer of dense connective tissue located beneath the mucosa. Microscopic Structure: Contains blood vessels, lymphatic vessels, nerves (Meissner's plexus), and submucosal glands. Function: Supports the mucosa, provides nutrients and oxygen to the mucosa, and facilitates nerve transmission.
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muscularis externa
3. Muscularis Externa: Gross Anatomy: A thick layer of smooth muscle responsible for peristalsis (movement of food through the GI tract). Microscopic Structure: Consists of two layers: Inner Circular Layer: Contracts to constrict the lumen. Outer Longitudinal Layer: Contracts to shorten the GI tract. Function: Peristalsis, mixing of chyme, and propelling food along the GI tract.
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serosa or adventitia
4. Serosa or Adventitia: Gross Anatomy: The outermost layer, covering the GI tract. Microscopic Structure: Serosa: A layer of peritoneum (mesothelium) and connective tissue that lines the abdominal cavity. Adventitia: Loose connective tissue that anchors the GI tract to surrounding tissues. Function: Protection, lubrication, and anchoring the GI tract to surrounding
47
what is the peritoneal cavity
The peritoneal cavity is the potential space within the abdomen, lined by the peritoneum, a serous membrane with two layers: the parietal peritoneum lining the abdominal wall and the visceral peritoneum covering the organs. Serous fluid lubricates the space, allowing organs to move freely  The peritoneum is a thin, continuous membrane that lines the entire abdominal cavity and covers the abdominal organs.  Parietal peritoneum: Lines the inner surface of the abdominal and pelvic walls, as well as the diaphragm.  Visceral peritoneum: Covers the abdominal organs, including the stomach, intestines, liver, and spleen
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what does the peritoneum do
* Support and Fixation: The peritoneum helps support and hold abdominal organs in place. * Lubrication: It secretes a thin layer of serous fluid into the peritoneal cavity, which acts as a lubricant, allowing organs to move smoothly during digestion and other activities. * Protection: It acts as a protective layer for the abdominal organs. * Pathways: It provides pathways for blood vessels, lymphatic vessels, and nerves to travel to and from the abdominal organs
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peritoneal cavity
Location: The peritoneal cavity is the potential space located between the parietal and visceral peritoneum. Structure: It's a space that normally contains a small amount of serous fluid. Function: o Lubrication: The serous fluid within the peritoneal cavity allows the abdominal organs to move freely and without friction. o Protection: It cushions the abdominal organs from injury. o Space for Expansion: The peritoneal cavity provides space for the expansion of organs, such as the stomach and intestines, during digestion
50
serous fluid
* Location: The peritoneal cavity contains a small amount of serous fluid. * Structure: It's a watery fluid that is secreted by the mesothelial cells lining the peritoneum. * Function: o Lubrication: The serous fluid lubricates the peritoneal surfaces, allowing organs to move smoothly against each other. o Shock Absorption: It helps to absorb shocks and protect the abdominal organs. o Fights infection: The antibodies in the fluid fight infection
51
mesentery
o The mesentery is a double-layered fold of peritoneum that attaches the intestines to the posterior abdominal wall, suspending them and providing a pathway for blood vessels, nerves, and lymphatics. Its functions include supporting the intestines, facilitating their movement, and housing essential structures like lymph nodes
52
mesentery proper
o Location: A fan-shaped, double-layered fold of peritoneum that attaches the jejunum and ileum (parts of the small intestine) to the posterior abdominal wall. o Function: Suspends the small intestine from the abdominal wall and carries its blood vessels, nerves, and lymphatics.
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mesocolon
o Location: The mesentery that attaches the colon to the posterior abdominal wall. o Types: Includes the transverse mesocolon (attaches the transverse colon), and other mesocolons for the ascending and descending colon. o Function: Suspends the colon from the abdominal wall and carries its blood vessels, nerves, and lymphatics.
54
greater omentum
o Location: A large, apron-like fold of visceral peritoneum that hangs down from the greater curvature of the stomach, passing in front of the small intestines and connecting to the transverse colon. o Function: Covers the small intestine loops, and is a common site for inflammatory and neoplastic processes.
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lesser omentum
o Location: A double layer of peritoneum that extends from the liver to the lesser curvature of the stomach and to the first part of the duodenum. o Function: Supports the liver and stomach, and contains the portal triad (hepatic artery, portal vein, and bile duct
56
Explain the difference between an intraperitoneal and a retroperitoneal organ.
o Intraperitoneal organs are completely enveloped by the visceral peritoneum and reside within the peritoneal cavity, while retroperitoneal organs are located behind the peritoneum, only partially covered by the parietal peritoneum, and are fixed to the posterior abdominal wall