Lecture 18 - Esophagus, Pancreas And Stomach Flashcards
What are some common chief complaints for GERD?
Odynphagia, pyrosis, CP, dysphagia, regurgitation, chronic cough, wheezing, sour taste, halitosis
What is the possible progression of GERD?
GERD —> reflux esophagitis —> esophageal stricture —> Barrett’s esophagus —> esophageal adenocarcinoma
What are the alarm sx for GERD?
New onset of sx >60 years of age
New IDA
Dysphagia, odynphagia, weight loss, evidence of bleeding (hematemesis, melena)
What are the sx of erosive esophagitis?
More severe than GERD sx
Odynphagia, retrosternal CP, dysphagia
Requires endoscopy for official diagnosis
How is GERD diagnosed?
Based off clinical hx and PE
Sx improve with empiric Tx (PPI, H2 blockers)
Ambulatory 24-48h pH monitoring
Endoscopy
What is the tx for GERD?
Lifestyle modifications
Acid suppression with PPI
Surgery
What is the tx for esophagitis?
Treat underlying cause (infectious, GERD, EoE)
PPI therapy
Sucralfate? Local anesthetic?
What is the tx for strictures?
Dilate with boogie Prevent recurrence (often time same cause as esophagitis)
What are some common chief complains for PUD?
Epigastric pain (DU pain awakening pt from sleep and hours after eating; GU mins after eating)
Bloating
Early satiety
N/V
Bleeding (hematemesis, hematochezia, melena)
What are the sx of gastroparesis?
Nausea, vomiting, abd pain (rarely predominant sx)
Early satiety
Bloating
What are the risk factors for PUD?
NSAIDs, H pylori, tobacco use, COPD, CKD, CAD
What are risk factors for gastroparesis?
DM, meds, viral (CMV, EBV, VZV, Norwalk, rotavirus)
Post surgical, scleroderma
Paraneoplastic dysmotility (small cell lung cancer)
What are the complications that can occur with PUD?
Bleeding (RF associated with poor outcomes include, >60 y/o, NSAID use, concomitant multi organ failure, pulmonary complications, malignancy)
Perforation
Gastric outlet obstruction (rare)
What can provide both diagnostic and therapeutic solutions for PUD?
EGD
What is the Tx for PUD?
Resuscitation if indicated (fluids and blood products)
Stop NSAIDs
Treat H pylori
PPI* (gold standard for tx)
Endoscopic therapy or surgical intervention