Lecture 17 Parkinson's Disease and its Treatment Flashcards
1
Q
What controls the ability to initiate and execute movements?
A
The basal ganglia
2
Q
Substantia Nigra contains what?
A
Dopamine producing neurons that project to the caudate nucleus and putamen.
3
Q
What is the caudate nucleus and putamen collectively known as?
A
The striatum
4
Q
What is the pathway of from the SN to the striatum?
A
Nigrostriatal pathway
5
Q
Parkinsons disease
A
Neurodegenerative disease caused by progressive loss of SN dopamine neurons,
6
Q
What are the symptoms of parkinsons disease?
A
Tremors at rest
Akinesia or bradykinesia
Rigidity
Postural instability & gait abnormalities
7
Q
What is the mean age of onset?
A
60, mortality usually caused by pneumonia or other infection
