Lecture 17: Basal Ganglia

Question 1

What is the basic function of the basal ganglia?

Answer 1

movement modulation

Question 2

What separates the putamen and the caudate nucleus?

Answer 2

the internal capsule

Question 3

Somatic Basal Ganglia

Answer 3

• Aka. Dorsal Basal Ganglia

- Consists of: Caudate, Putamen Globus Pallidus

Question 4

Limbic Basal Gangli

Answer 4

• Aka. Ventral Basal Gangli

- Consists of: Nucleus Accumbens & Olfactory Tubercle, Ventral Pallidum

Question 5

What type of neuron makes up 95% of the striatum?

Answer 5

spiny neurons

Question 6

Describe the axon of spiny neurons.

Answer 6

It is long and leaves the striatum.

Question 7

Describe the axon of aspiny neurons.

Answer 7

Short and do not leave the striatum.

Question 8

What is another name for spiny neurons?

Answer 8

projection neurons

Question 9

What is another name for aspiny neurons?

Answer 9

local circuit neurons or interneurons

Question 10

Where do spiny neurons that produce ENK project to?

Answer 10

From the putamen to the GPe

Question 11

Where do spiny neurons that produce substance P project to?

Answer 11

From the putamen to the GPi.

Question 12

What do spiny neurons projecting to the substantial nigra predominately contain?

Answer 12

Substance P

Question 13

What is the main function of the striatal neurons that project to the GPi?

Answer 13

promote limb movement

Question 14

What is the main function of the striatal neurons that project to the pars reticulata of the SN?

Answer 14

promote eye movement

Question 15

What is the main function of the striatal neurons that project to the pars compact of the SN?

Answer 15

regulate DA neurons

Question 16

What is the main function of the striatal neurons that project to the GPe?

Answer 16

inhibit conflicting movement

Question 17

Which type of striatal neurons possess D2 receptors?

Answer 17

Striato-GPe