Lecture 16: Mammary Tumors Flashcards
What is the third most common tumor in cats?
Mammary Tumors
- Older cats
- Siamese
What is the most common tumor in intact dogs?
Mammary Tumors
- Lower incidence in US (young age OHE)
- Median age of 10-11 years (malignant) 7-9 years (benign)
- rare <5 years
- Many breeds predisposed
Hormonal Influence:
(T/F) Intact cats are 7x more at risk of mammary tumors
True
For Cats, at what age is an OHE no longer beneficial?
13-24 months (11%)
Hormonal Influence:
OHE has a ______________ before 3rd estrus in dogs
very protective effect
- NO protective effect after 3rd estrus or 2.5 years
Progesterone administration may lead to __________ formation
Benign nodule
- Uncommon
- 4-18% of dogs with MGT
- Diagnostic criteria: Rapidly growing, painful warm, firm, erythematous
- Systemically ill and risk of mets at diagnosis
- Poor prognosis: 6 months with radiation and NSAID’s
Inflammatory Carcinoma
(T/F) FNA of masses can help to differentiate between malignant vs benign
False, no differentiation malignant vs benign, confirm mammary origin
Surgical Dose (Dog):
Masses < 1cm, superficial, not fixed
Lumpectomy
Surgical Dose (Dog):
Masses >1cm, central mammary mass
Mammectomy
Surgical Dose (Dog):
Masses in adjacent glands (glands 1-3 or 3-5)
Regional Mastectomy
Surgical Dose (Dog):
Multiple masses in multiple glands on same side
Unilateral Chain Mastectomy
Surgical Dose (Dog):
Masses in multiple glands bilaterally
Bilateral Chain Mastectomy
(T/F) Piroxicam (NSAID) and radiation is good for inflammatory carcinoma
True
Biologic Behavior (Cats):
(T/F) 80% malignant/ 20% benign
True
Biologic Behavior (Cats):
(T/F) Highly metastatic and size is prognostic
True
Prognosis (cats):
Size: <2cm
Median survival:
> 3years
Prognosis (cats):
Size: 2-3 cm
Median survival:
2 years
Prognosis (cats):
Size: >3 cm
Median survival:
4-6 months
What is the recommended treatment for cats?
Chain Mastectomy
- Increased Disease free interval
- But NOT increased survival time
- Chemotherapy Recommended: Doxorubicin
For which surgical dose on a cat would you need to perform staged surgeries?
Bilateral
Surgical Options:
In what specie is a lumpectomy ok & surgical dose is appropriate to dz?
Dogs
Surgical Options:
In what specie is bilateral staged chain mastectomy recommended?
Cats
> ____ cm is a poor prognosis for both cats and dogs
3
Definition:
Poor prognosis, generally not surgical
Inflammatory Carcinoma
