Lecture 16: Mammary Tumors Flashcards

1
Q

What is the third most common tumor in cats?

A

Mammary Tumors
- Older cats
- Siamese

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2
Q

What is the most common tumor in intact dogs?

A

Mammary Tumors
- Lower incidence in US (young age OHE)
- Median age of 10-11 years (malignant) 7-9 years (benign)
- rare <5 years
- Many breeds predisposed

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3
Q

Hormonal Influence:
(T/F) Intact cats are 7x more at risk of mammary tumors

A

True

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4
Q

For Cats, at what age is an OHE no longer beneficial?

A

13-24 months (11%)

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5
Q

Hormonal Influence:
OHE has a ______________ before 3rd estrus in dogs

A

very protective effect
- NO protective effect after 3rd estrus or 2.5 years

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6
Q

Progesterone administration may lead to __________ formation

A

Benign nodule

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7
Q
  • Uncommon
    • 4-18% of dogs with MGT
  • Diagnostic criteria: Rapidly growing, painful warm, firm, erythematous
  • Systemically ill and risk of mets at diagnosis
  • Poor prognosis: 6 months with radiation and NSAID’s
A

Inflammatory Carcinoma

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8
Q

(T/F) FNA of masses can help to differentiate between malignant vs benign

A

False, no differentiation malignant vs benign, confirm mammary origin

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9
Q

Surgical Dose (Dog):
Masses < 1cm, superficial, not fixed

A

Lumpectomy

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10
Q

Surgical Dose (Dog):
Masses >1cm, central mammary mass

A

Mammectomy

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11
Q

Surgical Dose (Dog):
Masses in adjacent glands (glands 1-3 or 3-5)

A

Regional Mastectomy

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12
Q

Surgical Dose (Dog):
Multiple masses in multiple glands on same side

A

Unilateral Chain Mastectomy

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13
Q

Surgical Dose (Dog):
Masses in multiple glands bilaterally

A

Bilateral Chain Mastectomy

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14
Q

(T/F) Piroxicam (NSAID) and radiation is good for inflammatory carcinoma

A

True

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15
Q

Biologic Behavior (Cats):
(T/F) 80% malignant/ 20% benign

A

True

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16
Q

Biologic Behavior (Cats):
(T/F) Highly metastatic and size is prognostic

A

True

17
Q

Prognosis (cats):
Size: <2cm
Median survival:

A

> 3years

18
Q

Prognosis (cats):
Size: 2-3 cm
Median survival:

A

2 years

19
Q

Prognosis (cats):
Size: >3 cm
Median survival:

A

4-6 months

20
Q

What is the recommended treatment for cats?

A

Chain Mastectomy
- Increased Disease free interval
- But NOT increased survival time
- Chemotherapy Recommended: Doxorubicin

21
Q

For which surgical dose on a cat would you need to perform staged surgeries?

A

Bilateral

22
Q

Surgical Options:
In what specie is a lumpectomy ok & surgical dose is appropriate to dz?

A

Dogs

23
Q

Surgical Options:
In what specie is bilateral staged chain mastectomy recommended?

A

Cats

24
Q

> ____ cm is a poor prognosis for both cats and dogs

A

3

25
Q

Definition:
Poor prognosis, generally not surgical

A

Inflammatory Carcinoma