Lecture 15 and 16: Folliculogenesis and the Estrous Cycle

Question 1

Major Feedback Event in Diestrus Stage

Answer 1

follicles grow but no ovulation occurs becuase of the negative feedback of progesterone on the GnRH surge center
the corpus luteum, however, is a transient gland and will be destroyed after luteolysis

Question 2

Major Feedback Event in estrus stage

Answer 2

frequency of GnRH pulses increases gradually with the (+) feedback of estradiol in the surge center, leading to a surge in GnRH

pattern of LH secretion follows a pattern of GnRH secretion and a surge in LH also occurs

the preovulatory surge of LH causes ovulation lf large dominant follicles

Question 3

Recruitment

Answer 3

dependent on FSH

Question 4

Selection

Answer 4

dependent on acquisition of LH receptors in the granulosa cells

Question 5

Dominance

Answer 5

dependent on LH

Question 6

Functions of Progesterone

Answer 6

negative feedback on hypothalamus and pituitary

negative feedback on uterine muscle contraction –> ensure implantation

positive feedback on histotroph secretion and general activity of endometrium