Lecture 15 Flashcards
Nervous Tissue
What cellular structure holds the nucleus?
Cell body
What are the extensions off the cell body called?
Dendrites
What is the origin of the axon, where the AP is generated?
Axon hillock
Describe the axon
- usually one per neuron
- VG channels, AP
- mitochondria and MT
- no nissel bodies, Golgi or RER.
- terminates in telodendrites
What is the pathway to the CNS called?
Afferent or sensory
What is the pathway away from the CNS called?
What are its divisions?
- Efferent, motor
- Somatic - goes to skeletal m
- Autonomic - goes to smooth muscle, cardiac muscle and glands
_____ is completely contained in the CNS.
Interneuron
Neurons can be named on number of processes.
1) Multipolar
2) Bipolar
3) Pseudounipolar
1) Single axon, multiple dendrites
2) 2 processes, (at each end of cell body) - special senses
3) single process form cell body that bifurcates towards CNS and out to periphery
Neurons can be named based on length of axon:
1) Golgi I
2) Golgi II
1) long axons leaving grey matter
2) Short axons, ramify thru grey matter (so they don’t leave it)
1) _____ is a bundle of axons in PNS
2) _____ is a bundle of axons in CNS
3) _____ is an aggregation of cell bodies and dendrites in the PNS.
4) _____ is an aggregation of cell bodies and dendrites in the CNS.
1) Nerve
2) Tract
3) Gaglion
4) Nucleus
1) What surrounds entire nerve?
2) What surrounds fascicles?
3) What surrounds the individual fibers and Schwann cells?
1) Epineurium
- type 1 collagen
2) Perineurium
- dense CT
- fibroblast are connected via tight jxns (zona occuludens)
- blood nerve barrier also linked by tight junctions
3) Endoneurium
- type 3 collagen
What are the 4 membrane specializations of neurons?
Receptors, ion channels, presynaptic membrane and postsynaptic membrane
What direction is anterograde transport?
What organelle is involved?
Cell body toward distal end of axon
- Kinesin
What direction is retrograde transport?
What organelle is involved?
Axon toward cell body
- dynein
1) What are glial cells, where are they derived from, and what are the types?
Glial cells = non-neuronal, support/”glue” cells; support fxns in both CNS and PNS
- derived from embryonic neural crest (except for microglia)
- Astrocytes
- Oligodendrocytes
- Schwann cells
- Microglial cells
- Ependymal cells