Lecture 14: Cardiac Output and Blood Flow in Muscle Tissues Flashcards
What is cardiac output?
quantity of blood pumped into the aorta each minute by the heart
quantity of blood that flows through the circulation
sum of all the blood flows to all the tissues of the body
What is cardiac index?
cardiac output per square meter of body surface
normal human cardiac index: 3 L/min/m^2
What is the flick principle of blood flow?
used to calculate blood flow through an organ
What is the determining factor that controls how much blood the heart pumps out?
heart is demand pump
heart pumps out whatever blood comes back into it from venous system
amount of blood returning to the heart that determines how much blood the heart pumps out
What are the two pumps in the cardiovascular system?
left and right ventricles
What are the two circuits in the cardiovascular system?
pulmonary and systemic
_____ must be equal in the two circuits
flow, cardiac output and rate
All pressures are higher in the ________ circuit
systemic
Chemical composition in the pulmonary venous blood is similar to that of _______
systemic arterial blood
Chemical composition of venous blood entering the right atrium is the same as the composition of ____
pulmonary arterial blood
What factors directly affect cardiac output?
basic level of body metabolism
whether the person exercises
age
size of body
What is the normal cardiac output for men?
5.6 L/min
What is the normal cardiac output for women?
4.9 L/min
What is the normal cardiac output for a resting adult?
5 L/min
Under most normal non stressful conditions, cardiac output is controlled almost entirely by _____
peripheral factors that determine venous return
What is the Bainbridge reflex?
the atrial stretch reflex, responds to changes in blood volume as detected by stretch receipts in the right atrium
What do baroreceptors respond to?
changes in arterial pressure
What reflexes control heart rate?
bainbridge and baroreceptor
What factors causes hypereffective heart?
nervous stimulation
hypertrophy of heart
exercise via nervous system
what factors cause hypo effective heart?
increased arterial pressure
inhibition of nervous excitation of heart
pathological factors causing abnormal heart rhythm/rate
coronary artery blockage
valvular heart disease
congenital heart disease
cardiac hypoxia
What are the cardiac factors that can cause decreased cardiac output?
severe blood vessel blockage--myocardial infarction severe valvular disease myocarditis cardiac tamponade cardiac metabolic derangement
What are the non cardiac factors that can cause decreased cardiac output?
decreased blood volume acute venous dilation obstruction of large veins decreased tissue mass decreased metabolic rate of tissues
What are factors that affect venous return to the heart from the systemic circulation?
right atrial pressure
degree of filing of systemic circulation