Lecture 14 Flashcards
1
Q
Classification of Genetic Disorders
A
- Single gene
- Multifactorial diseases
- Chromosome disorders
- Mitochondrial disorders
- Somatic mutations
2
Q
Autosomnal dominance
A
3
Q
Autosomnal recessive
A
Cystic fibrosis
Recessive allele has no effect on organism’s phenotype if only 1 allele is present in genome
4
Q
Dominant allele
A
- Determines phenotype when 1 copy present in genome
5
Q
X linked inheritence
A
- Incidence much higher in male than female
- Transmitted from man to all daughters
- Gene never transmitted from father to son
- Son always inherits X chromosome from mother
6
Q
Multifactorial Inheritence
A
COmbination of small inherited variations in genes, environmental
Heart disease, diabetes, cancers
7
Q
Mitochondrial Inheritance
A
- Defect in oxidative phosphorylation
- ## Severe
