Lecture 13 - RCT Critical Appraisal 2

Question 1

What does stratify mean?

Answer 1

Stratify means to balance everyone out (if there’s an important characteristic we will stratify to make sure it’s balanced)

• Ex. kids who are prone to lots of ear infections - want to balance these out between the two groups
• Contributes to randomization

Question 2

If we believe the ____, we have to treat both groups the same

Answer 2

blinding

Question 3

What do we do if we have more than 1 primary outcome?

Answer 3

We are going to do Bonferroni adjustment .
Say we have 3 outcomes:
So alpha = 0.05/3 = 0.017