Lecture 10 - Relative Risks & Odd Ratios Flashcards
What is the formula for RR (relative risk) ?
RR = Probability of an event in treatment group / Probability of an event in control group
Treatment/Control !!!
How do you calculate EER (experimental event rate) ?
EER = treated with disease / (treated with disease + treated with no disease)
How do you calculate CER (control event rate) ?
CER = control with disease / (control with disease + control with no disease)
RR = ?
RR = EER/CER
How do we calculate RRR ?
RRR = [Absolute value (EER - CER)] / CER
RRR = 1 - RR
What is the point estimate for CI ?
- if it contains, we accept
- if it doesn’t, we reject
1 ?
slide 14
What is ARR??
ARR = absolute value of (EER-CER)
NNT ?
NNT = 1/ARR = 1/Abs(EER-CER)
NNT are always rounded ____ to the nearest whole number
up
*makes the result more conservative
look at slide 35
okay
What is the general formula for ODDS RATIO ?
odds ratio = [a/b] / [c/d] = ad/bc
What will be closer to 1 ? (RR or OR)
RR
If base line risk (risk of events in control group) is low (<30%), the difference between OR and RR is _____ to be important.
unlikely
If OR is near ___, the difference between RR and OR is unlikely to be important
1
If baseline risk is high, and OR is not near 1, then RR is ?
likely to be appreciably closer to 1 than OR