Lecture 13 - Enzyme Regulation & Bioenergetics Flashcards
What are the two main types of regulation?
Allosteric regulation
Reversible covalent modification
True or false? An unfavorable reaction cannot be driven forward by a favorable reaction
False, it CAN
Reversibly bind to regulatory molecules that alter the enzyme activity
Allosteric regulation
A group is added to the enzyme to modulate its activity, and this group can be removed to reverse the effects.
Reversible covalent modification
The binding of a _________ regulator increases activity in the absence of a __________ regulator increases activity.
Positive
Negative
The study of energy transductions in living systems
Bioenergetics
What’s the first law of thermodynamics?
Energy may change form, and maybe transported, but energy cannot be created or destroyed.
What’s the second law of thermodynamics?
The entropy of the universe will always increase
A measure of how far a reaction must go to reach equilibrium, when initial concentrations of each component are 1M, with standard state conditions
Standard free energy change, ΔG’°
What does the actual free energy change for a reaction depend on?
On the initial concentrations of substrates and products, and on the temperature.