Lecture 13

Question 1

hematopoiesis or hemopoiesis

Answer 1

process of blood cell production

Question 2

Erythropoietin (EPO)

Answer 2

hormone released by the kidneys that stimulates red blood cell developemnt

Question 3

stem cells

Answer 3

all formed elements are derived from a single population of hemocytoblasts

Question 4

what happens when hemocytoblasts divide

Answer 4

one daughter cell remains a hemocytoblast while the other differentiates into either a myeloid stem cell or a lymphoid stem cell

Question 4

Stem cells

Answer 4

all formed elements derived form single population of hemocytoblasts

Question 5

Myeloid stem cell becomes

Answer 5

proerythroblasts, myeloblasts, monoblasts, megakaryoblasts

Question 6

proerythroblasts

Answer 6

develop into red blood cells

Question 7

myeloblasts

Answer 7

develop into basophils, neutrophils and eosinophils

Question 8

monoblasts

Answer 8

develop into monocytes

Question 9

megakaryoblasts

Answer 9

develop into platelts

Question 10

what do lymphoblasts

Answer 10

lymphoid stem cells

Question 11

Lymphoblasts

Answer 11

develop into lymphocytes

Question 12

Red blood cells

Answer 12

-biconcave disc shape
-7.5 um in diameter
- no nucleus
- flexible and capable of bending allowing passing through
- contain hemoglobin, lipids, ATP, carbonic anhydrase

Question 13

RBC functions

Answer 13

• transport oxygen from lungs to tissues
• carbondioxide transported from tissues to lungs

Question 14

hemoglobin

Answer 14

protein consisting of four subunits

Question 15

Globin

Answer 15

each subunit composed of a single polypeptide

Question 16

Three typed of hemoglobin

Answer 16

oxyhemoglobin, deoxyhemoglobin, and carbaminohemoglobin

Question 17

embryonic and featal

Answer 17

have greater attraction for oxygen than adult

Question 18

Oxyhemoglobin

Answer 18

iron in
hemoglobin bound to oxygen; 4 per
molecule of hemoglobin; bright red in color

Question 19

Deoxyhemoglobin

Answer 19

hemoglobin not bound to oxygen dark red

Question 20

Carbaminohemoglobin

Answer 20

globin of
hemoglobin bound to carbon
dioxide.

Question 21

Erythropoiesis

Answer 21

• formation rbc, takes 4 days

Question 22

production of rbc

Answer 22

Myeloid stem cells → proerythroblasts → early erythroblasts
→ intermediate erythroblasts → late erythroblasts →
reticulocytes (released into the blood) → erythrocytes.

Question 23

Erythropoietin

Answer 23

hormone stimulates RBC production; produced
by kidneys in response to low blood O2 levels (hypoxia).