lecture 13 Flashcards
1
Q
why sequence genomes?
A
regulatory sequences, higher order structure, chromosome maintenance, comparative searches
2
Q
how is an organisms genomic sequence obtained?
A
breaking organsims genomic DNA into small fragments, obtaining sequencing from fragments, search for overlaps to reconstruct sequence
3
Q
what are characteristics of model organisms?
A
small genome, easy manipulation
4
Q
how many genes does the human genome contain?
A
30,000-40,000 genes
5
Q
what are the major issues identifying genes within genomes?
A
how big is a valid open reading frame + identification of RNA splice sites
