Lecture 12: DNA Replication Flashcards
1
Q
In which direction is DNA (or RNA) synthesized
A
In the 5’ to 3’ direction
2
Q
In Eukaryotic cells, where does DNA Replication occur
A
In the Nucleus
3
Q
When does DNA Replication happen
A
During interphase, before mitosis and meiosis
4
Q
What enzyme splits the DNA strands
A
Helicase.
(Does this by breaking H bonds)
5
Q
What is primase
A
An enzyme, a type of RNA polymerase, that makes an RNA
primer
6
Q
How many pairs of Chromosomes?
A
23
7
Q
What is the purpose of having AT rich Origins of Replication
A
AT rich reigons like the TATA boxes make it easier for Helicase to pull apart
8
Q
What does it mean for DNA to be semi-discontinous
A
It is made in small fractions called okazaki fragments. This allows DNA to be replicated in the 5’ to 3’ reigon
