Lecture 11: Pediatric Substance Use Flashcards
Substance Abuse Diagnosis
- maladaptive pattern os substance use leading to significant impairment or distress
a. failure to fulfill obligations (work/school/home)
b. recurrent substance-related legal problems
c. continued use despite continuing social problems caused by use
d. using when physically hazardous
Diagnostic Testing Substance Use
- self-report
- lab testing
- UDS
- Blood
- Breath
- Hair
- saliva
- sweat
Treatment Substance Use (6)
- treatment intensity should reflect severity of d/o
- often outpatient treatment
- family therapy is most researched-most comprehensive
- other psycollcial models
- pharmacologic
- relapse rates over 60% at 12 months after treatment
Depressive D/O (8)
- consistently sad or depressed
- anhedonia
- changes in appetite or sleep
- irritability or agitation
- fatigue
- hopelessness/helplessness/worthlessness
- poor concentration
- SI
DDX for Depressive D/O (5)
- anxiety
- untreated ADHD
- substance use
- bipolar
- medical conditions
Diagnosis and treatment depressive d/o (5)
- full psych eval is most useful tool
- mood and feeling questionnaire
- tx approach varies with severity/duration/comorbidity
- SSRIs
- black box warning to increase suicide ideation in patients ages 24 and under - Psychotherapeutic interventions
Separation Anxiety (6)
- developmentally inappropriate and excessive anxiety regarding separation from home or parent/caregiver
- 2%-4% of children and adolescents
- accounts for 50% of all anxiety referrals at this age
- linked to insecure attachments
- may be precipitated by loss separation
- actual or threatened - assoc. with parental anxiety and enmeshment
-enmeshment=parental/caregiver boundaries blurred
“icky” per lecturer
Generalized anxiety d/o (5)*
- excessive anxiety and worry most of the time for 6+ months causing significant distress and impairment in functioning
- estimated 3% of children and 6%-7% adolescents
- assoc. with familial anxiety d/o
- also assoc. with parents who are anxious, hypercritical, have high expectations
- can manifest as children asking a lot of questions
Avoidant Personality d/o
- pervasive social inhibition , a sense of inadequacy
- hypersensitivity to criticsm - leads to avoidance of involvement, preoccupation with rejection and low self-esteem
Social Phobia (6)
- marked, persistent fear of situations that involve potential scrutiny
- fear is severe enough to interfere with normal functioning
- prevalence of avoidant PD and social phobia together
- 9% or 1.1%
- ratio to girls to boys is 7:3
- often precipitated by traumatic event
- strong familial basis
Panic D/O
- recurrent, unexplained panic attacks followed by 1+ month changes in bx related to the panic attack
- can include agoraphobia
- not due to a substance
- base prevalence unknown
- 1st degree relatives of people with panic d/o meet criteria in 20-40% cases
Selective Mutism (6)
- consistent failure to speak in specific social situations where there is an expectations of speaking despite speaking in other situations
- interferes with educations/occupation
- estimated prevalence 0.08%-0.7%
- more girls and boys
- 1-5 years AOO
- manipulative, passive aggressive, reactive, phobic
Differential DX anxiety D.o (4)
- GI issues
- Chronic illness
- substance-induced anxiety
- ADHD
Diagnosis and Treatment Anxiety d/o
- diagnosis by complete psych assessment
- behavioral treatments
- CBT
- Desensitization
- exposure - Pharmacologic
- SSRIs
- SNRIs
- TCAs
- Benzo
Bipolar D/o (3)
- variable clinical presentation
- pediatric bipolar is mostly mild episodes, rapid cycling, or irritability
- can be difficult to differentiate from ADHD and other psychiatric d/o
Signs/Sx Bipolar D/O (8)
- severe irritability
- moodiness
- temper tantrums
- depression/anxiety
- hyperactivity
- increased self esteem
- increased goal-directed behavior
- psychosis
Hypothesized contributors bipolar d/o (2)
- biologic
- correlations between genetic and neuroimaging findings - family environment
- stress and abuse
Differential DDX bipolar d.o (10)
- ADHD
- Schizophrenia
- child-abuse
- non-mood-related emotional and bx disturbances**
- developmental delays
- delirium
- tumors
- infections
- seizure d/o
- substance use
Diagnostic testing bipolar d/o (4)
- comprehensive history
- consider developmental context
- psych testing may be beneficial
- possibly neuroimaging in the future
Treatment Bipolar D/O (4)
- mood stabilizers or atypical antipsychotics
- official recommendation
: lithium or depakote* - atypicals are very effective
- psychotherapeutic interventions (CBT)
* increased electrical activity, which also occurs in seizure d/o therefore, anticonvulsants can help
Suicidal/Self-injurious behavior (4)
- suicidal ideation vs. suicide attempt
- non-suicidal self-injurious behavior
- consider severity of ideation
- consider lethality of attempt
Epidemiology Suicidal/Self-injurious behavior (6)
- completion rare in children 5-14 yr.
- completed suicide in adolescents 15-19 years 3rd leading cause of mortality
- females attempt 2x more
- males complete 4x
- underlying psych d/o
- other rx
Treatment Suicidal/Self-injurious behavior (4)
- rx assessment
- focus on underlying d/o
- CBT or IPT
- pharmacologic
Child Maltreatment Dx
2
4 forms maltreatment
- legal definitions vary by state
- forms of maltreatment
a. neglect
- educational, physical, medical
b. physical abuse
c. sexual abuse
d. emotional abuse
Epidemiology child maltreatment
- 3 million CPS reports annually
- 60% neglect
- 20% physical abuse
- 10% sexual - 1,500 children die every year related to maltreatment
Factors assoc. with child maltreatment (4)**
- poverty
- financial stress
- poor housing
- social isolation
Dx Child maltreatment (3)
- interviews of child and patient
- explore credibility
- psych testing
Treatment Child Maltreatment (3)
- maintain safety
- psychiatric tx for significant psych or bx symptoms
- trauma-focused CBT
PTSD Dx (8)
Infants-School aged children
infants-schoolchildren present as behavioral changes
- ease of feeding
- sleeping
- general settling
- regressed behavior
- unwillingness to explore
- increased aggression
- clinginess
- increased stranger danger
PTSD Dx
Primary-High school children (8)
similar to adult symptoms
- fear of death
- separation anxiety
- fear of the traumatic event
- nightmares
- sleep disturbances
- flashbacks
- fear of stimuli leading to event
- hyperarousal
DDX PTSD (2)
- depression
2. anxiety/ panic
Diagnosis & treatment PTSD (5)
- psych testing
- history
- SSRIs
- Alpha agonists
- psychological first aid
- *Does not depend on the event itself, dependent on child’s PERCEPTION of the event
- 2 children can go through the same event: one can get PTSD while one cannot
Tourette’s Dx (5)
- TIC: sudden rapid, recurrent, nonrhythmic, stereotyped, movement of vocalization
- tics occur many times a day ( usually in bouts) nearly every day for more than 1 year
- never tic free for more than 3 consecutive months
- onset before age 18
- not due to substance or medical condition
Epidemilology/etiology Tourette’s (7)
- transient tics comon in school aged children
- chronic motor tics 1/4
- 2x likely in boys
- seemingly strong heritability
- stress-sensitive
- increasingly aware of urges and exercise some control as they get older
- evidence implicates basal ganglia and corticosteroid thalamocortical abnormalities
DDX tourette’s (3)
- distinguish from movement d/o caused by medical conditions
- MS, Head injury, huntington’s - r/o PDD
- r/o OCD
- r/o extrapyramidal side effects from antipsychotics
DX Tourette’s (2)
- clinical rating scales
- Yale global tic severity scale
- preferred for assessing initial severity and measuring changes - direct observation
- most objective measure of severity
Treatment Tourette’s (8)
- goal is to diminish sx, not eliminate
- best to treat overall, long-term severity over exacerbation
- treat comorbidities first
- education and support
- D2(dopamine) antagonists (atypical)*best
- alpha agonists
- habit reversal training
- surgical intervention for adults with intractable tics (DBS)
OCD DX (6)
- obsessions
- compulsions
- time consuming and interfere with normal routine (1+ hour/day)
- often kept hidden by children
- in young children, parental observation of compulsive bx may be only definite sign of d/o
- content of obsessions/compulsions is not due to another axis I dx
Obsessions
intrusive thoughts, images, impulses that cause anxiety of distress
Compulsions
repetitive behavioral or mental rituals that the person feels driven to perform due to the obsession
epidemiology/etiology OCD (4)
- adolescent prevalence between 1.9%-3.3%
- seems to come from abnormalities of serotonin
- some heritability
- high prevalence of comorbidities
DDX OCD (6)
- MDD
- GAD
- body dysmorphia
- specific phobia
- hypochondria
- autism/PDD
Dx and treatment OCD (4)
- observation
- children’s yale-brwon obsessive compulsive scale
- CY-BOCS - CBT
- SSRIs
- fluoxetine
- sertraline
- fluvoxamine
- paroxetine
- citalopram
Possible indicators of sexual abuse
- bedwetting
- accidents
- check for patterns of accidents, or time frame where accidents are happening