lecture 11

Question 1

maybe this one table we will memorise

Answer 1

in the embryonic stage, we need to have the trachea and the oesophagus separated

we need surfactant and thats from 24 weeks that it starts to appear

we need the anatomy to be there as well of the blood air barrier.

Question 2

what is pulmonary surfactant comparised of and draw it

Question 3

surfactacnt proteins?

Answer 3

i meannnnn

Question 4

degradation and catabolism

Answer 4

type 2 pneumocyes producing phosophlipids and monolipids at the bottom of the lung the surface tension will be lower than further up the airway

if you have something in an area of low surface tension it will move to a high area of surface tension

Question 5

what ist he relationshup between smoking and surfactant

Answer 5

particles of smoke going down the airways, will be moved to ciliated airways by the surfactant and you will end up coughing up those particles instead of letting them travel further down

Question 6

surfacant facts?Hailey Bieber

Answer 6

Question 7

what ist he effect of pulmonary surfactant on surface tension?

Answer 7

imagine you have water molecules (high surface tension) the phospholipids interfere with this space and then take over and the surface tension is lowered from 70 to 10 mNm-1

that 10

Question 8

what is compliance? which is total pressure determined by

Answer 8

change in volume/change in pressure

total pressure is the alveolar pressure substracted by the intrapleural pressure

Question 9

what is the difference between saline filled vs air filled

Answer 9

saline eliminates the surface tension component which decreases volume and pressure?

Question 10

host defense?

Question 10

Law of Laplace

Answer 10

you can have small alveoli only because you can reduce the surface tension,

Question 10

fluid balance?

Question 10

what are the functions of pulmonary surfactant

Question 11

reduction of formation and maintenance of liquid plugs?

Answer 11

surfactant aids this?

Question 12

neonatal respiratory distress syndrome - what are the things that have resulted in less people dying from it

how do you treat it?

Answer 12

ventilators or providing surfactant therapy

Question 12

surfactant dysunfction results in ?

Answer 12