lecture 11

Question 1

ebola is a

Answer 1

filovirus
enveloped
RNA virus

Question 2

ebola effects which cells

Answer 2

DCs and macrophages

Question 3

ebola causes cytokine storm by

Answer 3

macrophages

Question 4

what binds to the macrophages to cause cytokine storm

Answer 4

shed glycoproteins

Question 5

immunity can be

Answer 5

active or passive

Question 6

active immunity is

Answer 6

if we get vaccinated or we are exposed to the pathogen

Question 7

passive immunity is

Answer 7

foetus gets immunity across the placenta
or from breast feeding

Question 8

what is the first class of antibody to be produced

Answer 8

IgM then switches IgG

Question 9

what is R0

Answer 9

the number of people in an unprotected population an infected person can transmit the disease to

Question 10

threshold

Answer 10

the percentage of the population that needs to be vaccinated in order to protect the entire population

Question 11

5 types of vaccinations

Answer 11

inactivated (dead) organisms
attenuated (live but virulence) organisms
subunit vaccines (protein fragments)
toxoid (bacterial toxin)
conjugate

Question 12

dead/inactivated organisms example

Answer 12

polio vaccine

Question 13

attenuated vaccine example

Answer 13

small pox
MMR

Question 14

cons of live/attenuated vaccine

Answer 14

could reverse to virulence

Question 15

subunit vaccine example

Answer 15

hepatitus B vaccine

Question 16

conjugate vaccine example

Answer 16

Haemophilus influenza type b

Question 17

adjuvants boost up the vaccine by

Answer 17

creating a depot and localise swelling, help recruit and activate cells