Lecture 10 - Cardiovascular responses to stress Flashcards
cardiac output equation
heart rate x stroke volume
usually 72 x 0.07 L = 5L/min
what is a more ideal measurement than cardiac output?
mean arterial pressure
mean arterial pressure equation
cardiac output x total peripheral resistance
what is total peripheral resistance
how much vessels are squeezing
how does heart regulate itself to respond to changes?
increase preload - increase stroke volume
decrease in preload - decreases stroke volume
preload best measured as EDV
how is edv measured?
echo
what does a very high preload result in
decrease in stroke volume
what can increase the preload?
increase in circulating volume - overhydration/fluid
increase in central venous pressure - increases amount of blood in heart
eg. respiratory pump
decrease in venous compliance
increase in atrial filling or contraction - atrial fibrillation
decreased heart rate - prolongs diastole
increases in aortic or pulmonary pressure
Intrinsic regulation in cardiac function is done by what effect?
Bowditch effect
What is the bowditch effect?
relationship between heart rate and cardiac performance
What does the bowditch effect suggest?
increase in heart rate - increase in force of contraction
decrease in heart rate - decrease in force
high levels of heart rate - eventually leads to a decreased force of contraction
How is bowditch independent to frank-starling?
length of the muscle is not affected
How does the extrinsic regulation of cardiac activity work?
autonomic - sympathetic and parasympathetic system
What does the sympathetic nervous system supply importantly?
the heart, kidneys and the adrenal gland
What does the parasympathetic system innervated
innervates the heart but not kidneys or suprarenal glands