lecture 10/11 Flashcards
meninges
- are tissue mebranes that lie between bones and soft tissues of the CNS
- protect and cushion the brain and spinal cord
the CNS is made up of
brain and spinal cord
Name the 3 tissues that make up the meninges of the brain
- dura mater
- arachnoid membrane (fluid filled)
- pia mater (thinest layer)
what fills the subarachnoid space
cebrebrolspinal fluid (CSF)
ventricles produce _______ at the ___________
- cerebrospinal fluid
- choroid plexus (meeting of the capillaries and ependymal cells)
Functions of CSF
Physical and chemical protection:
- provides buoyancy and absorbs shock, we dont want to much CFS cause pressure will build up
- deliver (nutrients like glucose and oxygen) and remove waste (CO2)
name one major difference between plasma and CSF
the lack of protein in CFS
CSF production
ependymal cells will selectivly transport solutes (ex. glucose —-> transcellular) and then water follows by osmosis
- make it at ependymal cells within ventricles that act as border control that regulates what can come in and what cannot
CSF absorption
CSF is absorbed from the subarachnoid space into venous circulation by the arachnoid villi
the 2 aspects of the blood-brain barrier
- the ependymal cells make up and important part of the BBB where CSF is produced at choroid plexus within the ventircles
- the astrocyte foot processes secrete paracrine which promote up regulation of tight junctions which causes lining of capillaries to link more tightly —-> no leaks!
metabolic needs of neurons and glial cells
- oxygen
- nutrients: glucose or ketone produced by the liver when carbs are low
how do oxygen and glucose cross the blood-brain barrier?
oxygen: diffusion
glucose: transcellular or glucose transporter in ependymal cells
white matter
- fats
- tracts of myelinated axon fibers
grey matter
- everything else
- dendrites, synapses, cell bodies
gray matter of the spinal cord
dorsal=sensory=afferent (incoming information —> to brain)
ventral=motor=efferent (outgoing information —> info coming from the brain leaving ur spinal cord)
white matter on the outside