Lecture 1 - Pipeline for X-ray structure determination

Question 1

Which structural technique is only good for small molecules?

Answer 1

NMR

Question 2

Which structural technique provides the highest resolution?

Answer 2

X-ray crystallography

Question 3

A crystal structure allows for _____ and _____ to be precisely measured

Answer 3

bond lengths; angles

Question 4

Two bottlenecks in crystallography

Answer 4

1. Expression of the target sample
2. Growing well diffracting crystals