Lecture 1-Neurotransmitters Of The GI Tract Flashcards
Acetylcholine-source?
Cholinergic neurons
Acetylcholine-actions?
- Contraction of smooth muscle
- Relaxation of sphincters
- Increased salivary secretion, gastric secretion, and pancreatic secretion
Norepinephrine-source?
Adrenergic neurons
Norepinephrine-actions?
- Relaxation of smooth muscle
- Contraction of sphincters
- Increased salivary secretion
Vasoactive intestinal peptide (VIP-same as GIP?)-source?
Neurons of the mucosa and smooth muscle
VIP-actions?
- Relaxation of smooth muscle
- Increased intestinal secretion and pancreatic secretion
Gastrin-releasing peptide (GRP)-source?
Neurons from gastric mucosa
GRP-actions?
Increased gastric secretion
Enkephalins-source?
Neurons of the mucosa and smooth muscle
Enkephalins-actions?
- Contraction of smooth muscle
- Increased intestinal secretion
Neuropeptide Y (NPY)-source?
Neurons of the mucosa and smooth muscle
NPY-actions?
- Relaxation of smooth muscle
- Increased intestinal secretion
Substance P-source?
Co-release with Ach from cholinergic neurons
Substance P-actions?
- Contraction of smooth muscle
- Increased salivary secretion