Lecture 1-Neurotransmitters Of The GI Tract Flashcards

1
Q

Acetylcholine-source?

A

Cholinergic neurons

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2
Q

Acetylcholine-actions?

A
  • Contraction of smooth muscle
  • Relaxation of sphincters
  • Increased salivary secretion, gastric secretion, and pancreatic secretion
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3
Q

Norepinephrine-source?

A

Adrenergic neurons

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4
Q

Norepinephrine-actions?

A
  • Relaxation of smooth muscle
  • Contraction of sphincters
  • Increased salivary secretion
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5
Q

Vasoactive intestinal peptide (VIP-same as GIP?)-source?

A

Neurons of the mucosa and smooth muscle

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6
Q

VIP-actions?

A
  • Relaxation of smooth muscle

- Increased intestinal secretion and pancreatic secretion

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7
Q

Gastrin-releasing peptide (GRP)-source?

A

Neurons from gastric mucosa

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8
Q

GRP-actions?

A

Increased gastric secretion

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9
Q

Enkephalins-source?

A

Neurons of the mucosa and smooth muscle

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10
Q

Enkephalins-actions?

A
  • Contraction of smooth muscle

- Increased intestinal secretion

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11
Q

Neuropeptide Y (NPY)-source?

A

Neurons of the mucosa and smooth muscle

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12
Q

NPY-actions?

A
  • Relaxation of smooth muscle

- Increased intestinal secretion

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13
Q

Substance P-source?

A

Co-release with Ach from cholinergic neurons

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14
Q

Substance P-actions?

A
  • Contraction of smooth muscle

- Increased salivary secretion

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