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PATH201 > Lecture 1 - Introduction To Pathology > Flashcards

Lecture 1 - Introduction To Pathology Flashcards

1
Q

What does PAS stain and what colour?

A

PAS stains glycogen magenta

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2
Q

What does Oil Red O stain and what colour?

A

Oil Red O stains Lipids bright red/nuclei blue

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3
Q

What does silver (Ag) stain and what colour?

A

Silver (Ag) stains nerves black

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4
Q

What does H&E stain and what colour?

A

Haematoxylin and Eosin (H&E) stains
• H: Nucleic acids blue
• E: stains elastic AND collagen pink

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5
Q

What does Van Giesen stain and what colour?

A

Van Giesen differentiates between elastin and other
connective tissues

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6
Q

What does Elastic Van Giesen stain in an artery and what colour?

A

Elastic Van Giesen - Artery: stains elastin black
and other connective tissue pink

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7
Q

What does Masson’s Trichrome stain and what colour?

A

Masson’s Trichrome –stains muscle, red blood
cells and keratin red, collagen blue, nuclei black

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8
Q

What is the function of simple cuboidal epithelia?

A

Simple cuboidal: protection from abrasion,
foreign material, invading material.
-Also protect from excessive water loss
due to semi-permeability

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9
Q

What is the function of pseudostratified columnar, ciliated epithelia in the respiratory tract?

A

Cilia clear secreted mucus that traps foreign material

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10
Q

What is the function of simple columnar epithelia?

A

Simple columnar: Ion transport of electrolytes

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11
Q

What is the structure and function of skeletal muscle?

A

Skeletal
• coordinated (striations)
• force generation (shape)

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12
Q

What is the structure and function of caridac muscle?

A

Cardiac
Intercalated discs for coordination of contraction

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13
Q

What is the structure and function of caridac muscle?

A

Spindle shaped (shaped like cigar) might wrap around arteries or blood vessels to help regulate diameter of vessels

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14
Q

What is the structure and function of adipose tissue?

A

Adipose
– Loose
– “designed” to hold lipids

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15
Q

What is the structure and function of bone tissue?

A

Bone
– Highly organised
– Strong and rigid for strength

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16
Q

What is the structure and function of tendon tissue?

A

Tendon
– Elongated fibres to transmit force
– Flattened cells to withstand pressure

17
Q

What are the key features of erythrocytes in a Giemsa stain?

A

Pink-red biconcave disc, anucleate

18
Q

What are the key features of monocytes in a Giemsa stain?

A

Large, mononuclear with kidney-shaped nucleus

19
Q

What are the key features of lymphocytes in a Giemsa stain?

A

Mononuclear, variable size and shape

20
Q

What are the key features of neutrophils in a Giemsa stain?

A

Segmented nucleus with 2-5 lobes, small purple-pink granules

21
Q

What are the key features of eosinophils in a Giemsa stain?

A

l 2-3 lobes, large orange-red granules

22
Q

What are the key features of basophils in a Giemsa stain?

A

2 lobes, large dark blue-purple granules obscure nucleus

23
Q

What are the key features of platelets in a Giemsa stain?

A

Small pale purple-blue cytoplasmic fragments with small purple granules

24
Q

What is the function of erythrocytes (RBCs)?

A

Transports O2 and CO2 (via Hb)

25
Q

What is the function of monocytes?

A

Phagocytosis (after transforming into macrophage)

26
Q

What is the function of lymphocytes?

A

Mediate immune response (B &T cells and NK cells)

27
Q

What is the function of neutrophils?

A

Phagocytosis

28
Q

What is the function of eosinophils?

A

Allergic reactions, defence against parasites

29
Q

What is the function of basophils?

A

Bind to IgE, release histamine to intensify inflammatory response

30
Q

What is the function of platelets?

A

Blood clotting

PATH201 (5 decks)

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