Lecture 1- Introduction Flashcards
3 major components of the MSK
bone
muscle
connective tissue
are all skeletal muscles voluntary
no- postural
function of bone
- Support
- Protection
◦Skull
◦Sternum
• Metabolic
◦Calcium and phosphate
• Storage
◦Calcium, phosphate and fat
- Movement
- Haematopoiesis
◦In adults
◦In babies liver and spleens
function of skeletal muscle
- Locomotion
- Posture
- Metabolic
- Store glycogen
- Venous return
- Deep veins in the legs
- Pumps blood back up to the heart
- Heat production
- E.g. shivering
- Continence
- Constant contraction of urethra and anus
function of conenctive tissue
- Tendons
- Force transmission muscle-bone
- High amounts of collagen, less elastin
- Stability of joints
- Force transmission muscle-bone
- Ligaments
- Support bone-bone
- Fascia (sheets of connective tissue) ◦Compartmentalisation ◦Protection
- E.g. deep fasica
- E.g. think of when we skinned the limbs
- Cartilage
- Articular
- Hyaline
- Very well hydrated
- Slippy
- Blue in colour
- Decrease friction
- Fibrocartilage
- Shock absorption
- Between the vertebra
- In the knee
- Increase bony congruity
- Synovial membrane
- Secretes synovial
- Bursa
- Synovial fluid-filled sacs to protect tendons, ligaments etc from friction
tendon
Force transmission muscle-bone
‣ High amounts of collagen, less elastin
‣ Stability of joints
ligaments
supports bone to bone
fascia
◦Compartmentalisation ◦Protection
‣ E.g. deep fasica
◦E.g. think of when we skinned the limbs
cartilage: articular
Hyaline
• Very well hydrated
- Slippy
- Blue in colour
‣ Decrease friction
cartilage: fibrocartilage
Shock absorption
Between the vertebra
In the knee
‣ Increase bony congruity
synovial membrane
secrete synovial fluid
bursa
synovial fluid- filled sacs to protect tendons, ligaments etc friction
bone connective tissue
ECM- fibres and ground substance
- In bone calcified - CaPO4(gives bone strength)
Bone is dense connective tissue
- Osteocytes
- Osteoblasts
- Osteoclasts
osteoblasts
lay down osteoid and build bone
how do osteoblasts build bone
Lay down bone and step back, lay down bone and step back
Traps osteoblasts in osteoid that is calcified—> osteocytes (trapped osteoblast in lacunae
osteocytes communicate via
via cytoplasmic processes (think cannuculi )
◦Transmit signals
osteocytes are important for
sensing stresses and strains in the bone
◦Will cause growth
◦Why exercise helps build bone
osteoblasts
◦Multinucleated
◦Related to macrophages
◦Release acidic substances and dissolve the bone —> releasing calcium
cortical bone strucutre (compact bone)
◦A bunch of pencils being held together ◦Haversion and volkmanns canals
classification of bone
long
short
flat
sesamoid
irregular
long bone
◦Bone longer than wide
◦Very good lever
◦Humerus
short
◦Bone as long as wide
◦Tarsals
◦Work together to give a range of movement
◦Gives points of attachment to for ligaments and tendons
flat
intramembranous ossification
◦For protection
◦Skull
◦Sternum
sesmoid
◦Protects tendons
◦E.g. patella
◦Shaped like a sesame seed
irregular
vetebra
bony prominences- muscle attachments
Areas where bones are close to the surface (called “bony prominences”) and areas that are under the most pressure are at greatest risk for developing pressure sores.
body prominences size
- Their size tells us about the muscle that attaches to it
- Small- not a powerful muscle that attaches
- If big site- must be a powerful muscle that attaches
grooves
related to nerves
- impression on bones- no free space in body
bone blood supply
each bone has multiple blood supply
Depending of let right dominance, bone will be
thicker in dominant arm/ leg • very dynamic
◦Due to osteoclasts and blasts