Lecture 1- Cartilage Flashcards

1
Q

Family of connective tissue

A

Fat cells, smooth muscle cells, fibroblasts, chondrocytes, osteocytes

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2
Q

Role of cartilage in prenatal life

A

Skeletal template

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3
Q

Cartilage role in postnatal life

A

Bone growth

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4
Q

How does cartilage get its nutrients

A

Through diffusion of nutrients from blood vessels of nearby tissues. Cartilage is avascular.

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5
Q

Cells in cartilage

A

Chondroblasts- immature cartilage cells; not in lacunae

Chondrocytes- mature, embedded in matrix and surrounded by lacunae, secrete extracellular matrix

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6
Q

Components of the matrix

A

Chondroitin sulfate
Keratan sulfate
Hyaluronic acid

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7
Q

Hyaline cartilage

A

Most common
Rich in type II collagen fibers
Present in embryo and adults
Has a perichondrium except in articular cartilage and growth plate

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8
Q

Appositional growth

A

Deposition of new cartilage matrix by chondroblasts at perichondrial surface

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9
Q

Interstitial growth

A

Division off chondrocytes within lacunae; cartilage expands from within

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10
Q

Places where you might find hyaline cartilage

A

Growth plate, articular cartilage, trachea, and larynx

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11
Q

Articular cartilage

A
Located within joint spaces
Composed of hyaline cartilage
No perichondrium
Interstitial growth
Nutrients received from synovial fluid
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12
Q

Layers of articular cartilage

A
Superficial (tangential) layer
Transitional layer
Radial layer
Calcified cartilage
Bone
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13
Q

Tidemark

A

Junction between radial zone and calcified cartilage

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14
Q

Elastic cartilage

A

External ear, auditory tube, and epiglottis
Elastic fibers
Does not calcify

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15
Q

Fibrocartilage

A

Found in annulus fibrosis of intervertebral discs, symphisis pubis, insertions of tendons and ligaments, meninsci of stifle joint
Type 1 collagen fibers
No perichondrium

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