Lecture 1 Flashcards
What is an antigen
Cell surface markers that can recognise these and self or non-self. Provokes an immune response
What makes a good antigen (5)
- Size
- Complexity
- Foreignness
- Route of administration
- Dose
What in an immunogen
Stimulates an immune response
What is an antibody
Functional protein
What are antibodies make by
Specialised B lymphocytes
Where are antibodies found
In body fluid
What can antibodies help with
Diagnosis of many different types of diseases
What is an epitope
Sites within antigens (Ag) recognised by an Ab or another Ag receptor
What are the two different types of immunity
- Innate
2. Adaptive
Describe innate immunity
- Immediate
- Present before an infection and function increases following infection n
- Defenses in the body regardless of the invader
Describe Adaptive immunity
- Delayed
- Antibody and cell-mediated responses
- Highly specific
Compare innate immunity and adaptive immunity
Refer to lecture slide
What are the components of innate immune response (4)
- Genetic susceptibility
- Physical and chemical barriers
- Cells
- Proteins
What are the two types of adaptive immune response
- Humoral
2. Cell-mediated
Characteristics of adaptive immunity (5)
- Specificity - lymphocytes can recognise structural differences
- Diversity
- Memory - enhances the ability to respond to reinfection
- Self-limiting
- Tolerance
