Lecture 1

Question 1

What is the central dogma?

Answer 1

The central dogma explains the flow of genetic material from DNA to RNA to proteins. DNA is used as a template for replication (to make copies of itself) and to make RNA, and RNA is used as a template to make proteins. The central dogma applies to all three domains of life (bacteria, archaea, eukarya.

Question 2

Components of DNA/RNA

Answer 2

DNA: Nitrogenous bases (adenine, guanine, cytosine, thymine), deoxyribose, phosphate
RNA: Nitrogenous bases (adenine, guanine, cytosine uracil), ribose, phosphate

Question 3

Bases in ssDNA held together by ___ bonds between ___ and ___

Answer 3

• Covalent bonds

- Sugar and phosphate

Question 4

Complementary DNA strand held together by ____ bonds between ____

Answer 4

• weak, non-covalent bonds

- bases

Question 5

Building blocks of proteins?

Answer 5

Amino acids

Question 6

What does the peptide backbone consist of?

Answer 6

AA’s w/out side chains

Question 7

The 3D structure of a protein is dictated by

Answer 7

Its amino acid sequence