Lecture 1 Flashcards
Define homeostasis
Condition: body’s internal environment remains relatively constant w/in limits
Conditions of homeostasis:
- Optimum [ ] gases, nutrients, ions, and water
- optimal temperature and pressure for health of cells.
Define stress:
Any stimulus that creates an imbalance in internal environment
Most abundant cation in extracellular?
Na+ =sodium
Most abundant cation intracellular:
K+, potassium
Most abundant anion in the extracellular:
Chloride; Cl-
Define feedback system:
Circular situation in which the information about the status of something is continually reported to a central control region.
- feedback
Most common. Response that reverses the direction of the initial condition; stabilizes the diminishing original response. Ex: Arterial BP to inhibit HTN by barorecptor sending inhibition signal to medulla.
+ feedback:
Response that intensifies initial condition. Destabilizing. ONLY healthy ex: cervix stretching causes stronger uterine contractions.
How do you calculate gain in a feedback system?
[Control system response - uncontrolled response] / ERROR
What is error when calculating gain?
Error is the amt. of uncorrected increase in the CONTROLLED system
Describe cell membrane w/ respect phospholipids and proteins.
“Unit membrane” has cholesterol inserted among the phospholipids. Proteins are asso. W/ the membrane. Hydrophobic tails of phospholipid and hydrophilic head groups.
What characteristic is necessary to pass across cell membrane?
Lipid soluble (hydrophobic) substances can readily pass
Peripheral proteins
Loosely attached to one surface or the other of membrane. Easily removed. Can be anchored by GPI-proteins.
Integral proteins:
Inserted in one side or pass al the way through and are exposed on either side of membrane.
Functions of plasma membrane:
Defines the intra/extracellular fluid composition. Filters, information exchange between the cell and environment; ends/exocytosis