Lecture 1 Flashcards
Neurobiology
Studying the physiology, anatomy, and pathology of the nervous system
Neurophysiology
- Studying the chemical (i.e. genes and gene products) and electrical underpinnings of
nervous system function
• Neurophysiology requires understanding the anatomy
• Abnormalities in anatomy and physiology = pathology
Origin of the Nervous System:
Multicellularity has evolved _____ times…in who?
Multicellularity evolved independently three times
• Plants, animals and fungi
Origins of Nervous System:
Placozoans
lack nervous systems yet exhibit motile behaviors
Origins of Nervous System:
Porifera
- Sponges are arguably the most simple animals
- Once thought to be the earliest- diverging lineage
- Have choanocytes that resemble choanoflagellates
Origins of the Nervous System:
Ctenophores
most early- diverging animals
• might have evolved a nervous system independently
Chemical Synapses
reduce diffusion time and concentration requirements by
bringing pre- and post-synaptic structures close together
A diversity of neurotransmitter and neuropeptide types provide complexity for chemical synaptic transmission
Electrical Synapses
faster than chemical synapses
What constitutes a Nervous System?
A collection of synaptically connected neurons that:
• Sense and/or transmit information about different stimuli • light, sound, chemicals, temperature, touch and pain
• Process and store information
• Interpret sensory information, learn and create memories, retrieve memories, compile
neural processes to select appropriate actions
• Send effector outputs to…
• Muscle(forco-ordinatingmovement)
• Neuroendocrine cells (for altering physiology)
• Other cell/tissue types (e.g. circulatory, respiratory and reproductive systems)