Lecture 1 Flashcards
What are the 3 key components of the plasma membrane
Phospholipids, Cholesterol and proteins
What are the 3 key functions of the plasma membrane
Protection, Transport and communication
What are the 2 types of proteins in the plasma membrane and where are they found
Integral- anchored to the membrane
Peripheral- On inside or outside
What are the 3 parts of the cytoskeleton, describe them
Microtubules- made of tubulin, makes tubes, resists compression, largest, used in cell motility, maintains cell shape
Microfilaments- made of actin, makes ropes, resist tension, smallest one, Forms cortical network, important for movement
Intermediate filaments- made up of mainly keratin, makes cables, forms more permanent things, anchors organelles, really good at tension, important in cell adhesion
Describe Mitochondria function
Site of cellular respiration and ATP synthesis.
Describe nucleus function
Control centre, contains DNA- euchromatin and heterochromatin, contains nucleolus which makes rRNA and ribosomal subunits. Surrounded by the nuclear envelope which is double membrane and continuous with the rER.
Inner surface lined withd nuclear lamina, envelope is spanned by nucleoporins for transport in and out
What are the 3 parts of the endomembrane system and its function
ER, golgi and vesicles. Functions to modify, package and move proteins and lipids. Both in and out of the cell
sER
No ribosomes, Synthesises lipids, metabolises carbs. Detoxification, stores calcium ions
rER
Ribosomes. Modifies, folds and packages vesicles to transport to the golgi
Golgi apparatus
Series of membrane sacks and vesicles. Enter from rER in the cis face, get modified, glycosylated and sorted into other vesicles. Leave through trans face
Vesicles types and description
Membrane bound. Move along microtubules by walking with motor proteins. Transport vesicle-type 1, move contents within the cell. Secretory vesicles-type 2, move contents out of the cell via exocytosis. This is how signally molecules are released
