Lecture 1 Flashcards

1
Q

Began in the 12th Century
Process of cutting holes or drilling holes into the brain to “let the demons escape”

A

Trepanation

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2
Q

Used in the early 20th Century
Baths, packs and sprays were used
Warm Baths – were used for clients with insomnia, suicidal ideation, and to help to calm agitated clients
Cold Baths – were used for clients with Mania and Psychosis
Baths, showers and packs could last from 3 hours to a few days

A

Hydrotherapy

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3
Q

Used extensively in 1940’s and 1950’s
Process – clients received high levels of insulin to induce coma
After the “prescribed” amount of time the client was revived with an emergency dose of glucose

A

Insulin Shock Therapy

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4
Q

Metrazol or Cardiazol is a synthetic preparation of Camphor
Small doses of Camphor produce tachycardia, can act as a diuretic, reduce appetite and slow breathing
Large doses are lethal
Metrazol was used in 1935 by Ladislas von Meduna to induce coma in clients with Schizophrenia

A

Metrazol Convulsive Therapy

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5
Q

Created in the 1930’s by Egaz Moniz
Brain surgery that severed and damaged the prefrontal lobe.
Widespread until the end of the 1950s
Speculated that this type of surgery removed the harmful parts of the brain that contributed to Schizophrenia, Depression and Anxiety.

A

Prefrontal Lobotomy

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6
Q

Invented by Ugo Cerletti
Electric shock used to stimulate a seizure
Use of ECT started in the 1940’s and continues today
Practice today has changed significantly

A

Electroconvulsive Therapy

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7
Q

study of drugs that alter functions of living organisms.

A

Pharmacology

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8
Q

use of drugs to prevent, diagnose, or treat signs, symptoms and disease processes.

A

Drug Therapy

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9
Q

drugs given for therapeutic purposes.

A

Medications

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10
Q

the first drug of a particular drug class to be developed

A

Prototypes

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11
Q

is related to the chemical or official name and is independent of the manufacturer.

A

Generic Name

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12
Q

is the name that is designated and patented by the manufacturer

A

Brand (Trade) Name

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13
Q

Pre-clinical studies

Clinical trials

Drug submission to Health Products and Food Branch

Submission review

Market authorization decision

Public access

Surveillance and investigation

A

Regulatory Processes in Canada

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14
Q
  1. Right medication
  2. Right client
  3. Right dose
  4. Right route
  5. Right time and frequency
  6. Right documentation
  7. Right reason/assessment
  8. Right to refuse
  9. Right evaluation
  10. Right client education
A

Ten Rights of Medication Administration

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15
Q

Oral (PO, sublingual)
Intramuscular (IM)
Subcutaneous (Sub-Q)
Intravenous (IV)
Inhalation (nasal, oral)
Transdermal (topical)
Vaginal
Rectal
Enteral (Nasogastric, GI tube)
are all…

A

Routes of administration

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16
Q

Pharmacology textbooks
Drug Reference Books
(ex. Compendium of Pharmaceuticals and Specialties)
Journal Articles
Credible Internet Sites
(ex. Health Canada, Manitoba Health)

A

Sources of Drug Information

17
Q

may be defined as the study of the dynamic movements of foreign chemicals (xenobiotics) during their passage through the body and as such encompass the kinetics of absorption, distribution, biotransformation/metabolism and excretion

A

Pharmacokinetics

18
Q

Principles of ADME

A

Specific processes are:
Absorption
Distribution
Metabolism
Excretion

19
Q

Onset of drug action largely related to the rate of

A

Absorption

20
Q

medication form,
route of administration,
administration site,
blood flow,
GI function, and
presence of food and other drugs.

A

Factors that affect absorption

21
Q

depends on blood circulation

A

Distribution

22
Q

protein binding
blood-brain barrier
pregnancy
lactation

A

Distribution is affected by

23
Q

Method that drugs are inactivated or bio transformed by the body

A

Metabolism

24
Q

Active metabolites
Inactive metabolites
Prodrugs

A

Drugs are changed to

25
Q

Elimination of the medication from the body

A

Excretion

26
Q

____ depends on adequate function of:
kidneys and bowels
circulatory system
lungs
skin

A

Excretion

27
Q

the length of time it takes for ½ the dosage of a medication to be metabolized

A

Half Life

28
Q

What the drug does to the body or how the drug behaves in the body

A

Pharmacodynamics

29
Q

Most drugs exert their effect by chemically binding with receptors at the cellular level

A

Receptor Theory of Action