lec_10_H_Influence_of_systemic_disorders_on_the_Periodontiu_28_12

Question 1

The
number of……………………. increase with increased
levels of sex hormones in puberty

Answer 1

P intermedia Capnocytophaga

Question 2

The severity of gingivitis is increased during pregnancy in

Answer 2

the 2 nd or
3 rd month and reaches its peak in 8 th month (hormones rise to its
maximum in eight month)

Question 3

•

There is also a marked reduction in the severity of gingivitis occurs

Answer 3

2
months postpartum (decrease secretion of these hormones), and
after 1 year the condition of the gingiva is normal

Question 4

•

P. intermedia increase greatly due to

Answer 4

the increased levels of estrogen
& progesterone which substitute menadione (vitamin K); an essential
growth factor. Periodontitis during pregnancy increases the risk for
preeclampsia by 2 2.5 folds.

Question 5

•

Oral contraceptive pill contains

Answer 5

progesteron

often combined with an estrogen

Question 6

•
Metronidazole should not be prescribed to
females taking oral contraceptives to

Answer 6

avoid the
risk of drug interaction that can lessen the
contraceptive effect

Question 7

The gingiva remaining oral mucosa are dry, shiny and
vary in color from abnormal paleness to redness and easy
bleeding, burning sensation & altered taste

Answer 7

senile atrophic

gingivitis

Question 8

WBCs are involved in

Answer 8

inflammatory reactions

necessary for cellular defense against MO

Question 9

RBCs are responsible for

Answer 9

gas exchange
nutrient supply to the periodontal tissues
•

Question 10

Platelets are necessary for

Answer 10

normal hemostasis
as well as recruitment of cells during
inflammation and wound healing

Question 11

The leukemias are malignant neoplasias of WBCs precursors

characterized by

Answer 11

1.
Replacement of bone marrow with proliferating leukemic cells
(resulting in reduced production of RBCs, WBCs and platelets,
leading to anemia, leukopenia thrombocytopenia,
respectively)
2.
Abnormal numbers forms of immature WBCs in the
circulating blood
3.
Widespread leukemic cells infiltrate in the liver, spleen, lymph
nodes, other body sites

Question 12

Deep punched out ulcers covered by a white slough can be found
on

Answer 12

the oral mucosa, that occur at sites of trauma such as the buccal
mucosa

Question 13

blood disorder that results in low levels of

circulating neutrophils

Answer 13

Neutropenia

Question 14

neutropenic episodes of 1 week duration

every 3 weeks)

Answer 14

cyclic Neutropenia

Question 15

Agranulocytosis occurs if the counts drop below

Answer 15

500 /mm 3

Question 16

Causes of Neutropenia

Answer 16

1.
It can be genetic (Familial neutropenia
2.
Drug induced (e g patients receiving chemotherapy for cancer)
3.
It may immune either auto immune ( or allo immune
(from other person as after blood transfusion)
4.
2 ry to other disease as SLE lymphoma

Question 17

Neutropenia Effects

Answer 17

1.
Infections that may be life threatening
2.
Ulceration in the oral cavity, that is characterized by the
absence of a notable inflammatory reaction around ulcer
caused by lack of granulocytes (a striking feature)
3.
Gingival hemorrhage, necrosis, periodontitis fetid odor

Question 18

Systemic conditions associated with

neutrophil functional defects وقالت مهم وأسئلة وبتاع فاحفظ

Answer 18

slide 17/18 in pdf lecture

Question 19

IL-1 is catabolic cytokine that promotes

Answer 19

bone resorption and

collagen destruction

Question 20

Severe

vitamin C deficiency in humans results in

Answer 20

scurvy (defective collagen
formation a disease characterized by delayed wound healing hemorrhagic
diathesis Bleeding, swollen gingiva ( mobile teeth and increased
susceptibility to infection are oral features of scurvy

Question 21

PMN count in peripheral blood is

Answer 21

3000

6000 /mm 3

Question 22

Agammaglobulinemia

Answer 22

•
It is an immune deficiency resulting from inadequate antibody
production caused by a deficiency in B cells

Question 23

HIV associated Gingival & periodontal

diseases

Answer 23

•
1 . Linear gingival erythema
•
2 . Necrotizing ulcerative gingivitis
•
3 . Necrotizing ulcerative periodontitis
•
4 . Necrotizing stomatitis

Question 24

IL

1 is catabolic cytokine that promotes

Answer 24

bone resorption and

collagen destruction

Question 25

There

is association between IL 1 gene polymorphism &

Answer 25

advanced periodontal disease