Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Physiology Part 2 > Lec37_Physiology Testing in Respiratory Disease > Flashcards

Lec37_Physiology Testing in Respiratory Disease Flashcards

1
Q

What is FVC [forced vital capacity]?

A

volume of air a subject can exhale after maximal inspiration to total lung capacity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is FEV1 [forced expiratory vol in 1 sec]?

A

volume of air exhaled in first second of expiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is TV? What is normal value?

A

volume of air inhaled and exhaled during quiet breathing [500 mL]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is IRV? What is normal value?

A

additional volume that can be inspired above TV [3000 mL]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is ERV? What is normal value?

A

additional volume that can be expired below TV [1200 mL]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is RV?

A

residual volume

vol of gas in lungs after a maximal forced expiration [1200 mL]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is IC?

A

IC = TV + IRV

inspiratory capacity?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is FRC?

A

FRC = ERV + RV

- equilibrium vol of lungs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is VC?

A

VC = IC + ERV

- vol expired after maximal inspiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is TLC?

A

TLC = VC+RV

- total vol of air in lungs after max inspiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is average Pe max?

A

170 cm H2O

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is average Pi max?

A

-100 cm H2O

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is diffusing capacity? What is molecule used to assess? What is the limiting factor of its diffusion?

A
  • assess gas exchange ability of lungs
  • CO chosen because it binds hemoglobin with highest affinity
  • limiting factor is the status of alveolocapillary membrane
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is equation for diffusing capacity? maybe more than we need to know

A 
DLco = V.CO / PACO - Pc-Co]
DLco = diffusing capacity
V.CO = rate CO taken up by lung
PACO = partial pressure CO in alveoli
Pc-CO = capillary/venous pressure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What happens to FEV1 and FVC in obstructive lung disease like asthma? what about FEV1/FVC ratio?

A

air doesn’t come out fast, needs longer to plateau
much lower FEV1, slightly lower FVC
very reduced FEV1/FVC ratio
“scooping out” in flow vs volume graph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happens to FEV1 and FVC in restriction? what about FEV1/FVC ratio?

A

decreased FEV1 and decreased FVC

normal FEV1/FVC ratio

17
Q

What does the width of the triangle curve in flow vs volume curve signify?

A

FVC

18
Q

What happens to obstruction in flow vs volume graph?

A

relative total lung capacity increased after full breath but can’t get all the air out

  • hyperinflation = increased TLC
  • difficulty expiring = increased RV
19
Q

In restriction what happens to FEV1, FVC, FEV1/FVC, RV, and TLC in restriction?

A 
FEV1: very decreased
FVC: very decreased
FEV1/FVC: no change or slightly increased
RV: decreased
TLC: decreased
20
Q

In restriction what happens to FEV1, FVC, FEV1/FVC, RV, and TLC in obstruction?

A 
FEV1: very decreased
FVC: slightly decreased
FEV1/FVC: decreased
RV: increased
TLC: increased
21
Q

What are 3 examples of obstructive lung disease?

A
  • asthma
  • ephysema
  • chronic bronchitis
22
Q

what are 3 examples of restrictive lung disease?

A
  • interstitial lung disease [pulm fibrosis]
  • neuromuscular disease [weakness, myasthenia gravis]
  • obesity [because there push up on diaphragm making smaller lung vol]
23
Q

what 2 things can increase diffusing capacity?

A
  • more Hgb binding sites

- more blood flow to chest

24
Q

How does number of Hgb binding sites affect diffusing capacity?

A

more binding sites = high diffusing capacity

25
Q

How does blood flow to chest affect diffusing capacity?

A

more blood flow = high diffusing capacity

26
Q

Is asthma obstructive or restrictive lung disease?

A

obstructive

27
Q

What are 3 examples of obstructive lung disease?

A
  • asthma
  • ephysema
  • chronic bronchitis
28
Q

what are 3 examples of restrictive lung disease?

A
  • interstitial lung disease [pulm fibrosis]
  • neuromuscular disease [weakness]
  • obesity [because there push up on diaphragm making smaller lung vol]
29
Q

what 2 things can increase diffusing capacity?

A
  • more Hgb binding sites

- more blood flow to chest

30
Q

How does number of Hgb binding sites affect diffusing capacity?

A

more binding sites = high diffusing capacity

31
Q

How does blood flow to chest affect diffusing capacity?

A

more blood flow = high diffusing capacity

32
Q

Is asthma a obstructive or restrictive lung disease?

A

obstructive

33
Q

Is asthma obstruction reversible or irreversible?

A

generally reversible by bronchodilator/albuterol

34
Q

What happens to FEV1, FVC, FEV1/FVC, BD, and DLCO in asthma?

A 
FEV1: very decreased
FVC: decreased
FEV1/FVC: decreased
response to BD: good response
DLCO [diffusion capacity]: normal
35
Q

What happens to FEV1, FVC, FEV1/FVC, BD, and DLCO in emphysema?

A 
FEV1: very decreased
FVC: decreased
FEV1/FVC: decreased
response to BD: none
DLCO  [diffusion capacity]: decreased
36
Q

What happens to FEV1, FVC, FEV1/FVC, BD, and DLCO in chronic bronchitis [CB]?

A 
FEV1: very decreased
FVC: decreased
FEV1/FVC: decreased
response to BD: a little mixed
DLCO [diffusion capacity]: normal

Physiology Part 2 (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions