Lec 9: Nucleic Acids

Question 1

what link forms between a nucleobase and nucleoside?

Answer 1

β‐ N ‐glycosidic link

Question 2

what is the difference between a pyramidine and a purine?

Answer 2

purines contain two carbon-nitrogen rings and four nitrogen atoms

where as

pyrimidines contain a single carbon-nitrogn ring and 2 nitrogen atoms

Question 3

what are pyrimidine nucleotides? which base are pyrimidines?

Answer 3

Heterocyclic organic compounds consisting of a pyrimidine ring

cysosine (C), Uracil (U), thymine (T)

Question 4

what are purine nucleotides? which bases are purines?

Answer 4

Heterocyclic organic compounds consisting of a pyrimidine ring fused to an imidazole ring

adenine (A), guanine (G)

Question 5

name this molecule

Answer 5

ATP

Question 6

name this molecule

Question 7

name this molecule

Answer 7

datp

Question 8

name this molecule

Answer 8

ddatp

Question 9

what is GTP (Guanosine triphosphate) used for?

Answer 9

– Important in protein synthesis and cell signalling

Question 10

what is meant when it said that DNA strands are antiparallel?

Answer 10

– Strands are read 5’ to 3’

– Complementary strands have asymmetric ends

Question 11

what does this diagram show?

Answer 11

semiconservative replication

Question 12

what is a karyotype?

Answer 12

the number and appearance of chromosomes in the nucleus of a eukaryotic cell.

Question 13

what is the Central Dogma?

Answer 13

The central dogma states that information in nucleic acid can be perpetuated or transferred but the transfer of information into protein is irreversible”