lec 7

Question 1

Single Strand Repair
(1) Mismatch repair mechanism (MMR)

Answer 1

Repair errors that occur during replication
and are not removed by proofreading
DNA polymerase.

Question 2

Lynch syndrome or
Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is defect in ?

Answer 2

MMR

Question 3

defect of MMR lead to accumilation

Answer 3

lead to accumulation of somatic mutations in genes that are involved
in mismatch repair mechanism