lec 7 Flashcards
1
Q
Single Strand Repair
(1) Mismatch repair mechanism (MMR)
A
Repair errors that occur during replication
and are not removed by proofreading
DNA polymerase.
2
Q
Lynch syndrome or
Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is defect in ?
A
MMR
3
Q
defect of MMR lead to accumilation
A
lead to accumulation of somatic mutations in genes that are involved
in mismatch repair mechanism