LEC 6: Health Challenges in Labour and Birth Flashcards
Preterm Labour and Preterm Birth
- Leading cause of mortality and morbidity (around 75% to 85%)
- Rate of PTB is 7% in SK
- Incidence in USA is worse
- Rate of PTB is increasing
What is the rate of PTB increasing?
- Assisted reproductive technology (ART)
- Increasing role of infectionin PTL/ PTB
What causes preterm labour?
- Race
- Age extremes (<17 or >35)
- Smoking, alcohol, drugs
- Infection, inflamamtation, toxicology
- Stress
- Prenatal care, nutrition, and oral health
- Cervical surgery or abnormalities
- Placental problems (previa, abruption)
- Genetics
- Previous PTB (Most common cause)
- Hypertensive disorder of pregnancy
Risk Factors Associated with Preterm Labour and Birth
- African-American race
- More than double the risk
- Maternal age extremes
- Less than 16 years and more than 40 years old
- Low socioeconimic status
- Alcohol or other drug use, especially cocaine
- Poor maternal nutrition
- Maternal periodontal disease
- Cigaretter smoking
- History or prior preterm birth
- Triples the risk
- Uterine abnormalities
- Preexisting diabetes or hypertension
- Multiple gestation
- Premature rupture of membranes
- Late or no prenatal care
- Short cervical length
- Sexually transmitted infections: gonorrhea, Chlamydia, trichomoniasis
- Bacterial vaginosis
- 50% increased risk
- Chorioamnionitis
- Hydramnios
- Hypertensive disorders or pregnancy
- Cervical insufficiency
- Short interpregnancy interval: less than 1 year between births
- Placental problems, sucha s placenta previa and placental abruption
- Maternal anemia
- UTIs
- Intimate partner violence
- Stress, acute and chronic
Common Symptoms of Preterm Labour
- Low abdominal pain, cramps, backache
- Common symptoms
- Bleeding, spotting, show, ROM
- Pelvic pressure
- Baby pushing down
- Increased amount/ changes in vaginal discharge
- Contractions every 10 minutes or more often
- Thorough assessment and diagnosis is key
- Signs and symptoms of PTL are often subtle
Fetal Fibronectin ( ƒFN)
- Glycoprotein released into cervical/ vaginal fluid in response to inflammation or separationof amniotic membranes
- Normal in cervico-vaginal secretions until 22 weeks gestation and again near the time of labour
- Negative = lacck of ƒFN = pregnancy is likely to continue for at least another two weeks (98%)
- Positive ƒFN = present 24 through 34 weeks getationindicates increase risk of preterm delivery
- Absence is a better prodictor
- Not done on everyone- if they think its pre-term labour, then it is done
Managment of Pre-Term Labour (PTL)
- Need to ask- Should labour be stopped?
- Is mom bleeding?
- What is the gestational age of baby?
- Assess and monitor VS, contractions, fetus
- Avoid stimulation
- Vaginal exams, also increase risk for infection
- Sexual intercourse
- Nipple stimulation
- Keep bladder empty
- Bedrest
- Hydration- IV
- Magnesium sulfate
- Sedation
Managment of PTL: Tocolytics
- Indomathacin
- Anti-prostaglandin inhibits uterine activity
- Effective in delaying delivery x 48 hours
- Not recommended for long term use- PDA
- Calcium Channel Blockers- Nifedipine (Adalat)
- Blocks the passage of calcium which relaxes the uterine muscles
- Progesterone (in trials)
- May prevent and reduce incidence of PTB if previous history of PTB
Cervical Insufficiency (Incompetent Cervix)
- Premature painless dilation of cervix
- 20 to 28 weeks
- 2nd trimester abortions
- Anomalies of cervix
- DES, 2nd trimester abortions, invasive cervical biopsy
- Infections
- Multiple gestation, polyhydramnios
- Anomalies of cervix
- Diagnosis
- Heaviness in pelvic area
- Preterm Preamture Rupture of Membrane (PPROM)
- Ultrasound
Cervical Insufficiency Treatment
- Bedrest, pelvic rest, avoid heavy lifting
- Cervical cerclage (suture)
- Infection, blood loss, PPROM, preterm labour
- Damage to the cervix
- Not appropriate if vaginal bleeding, infection, uterine contractions, membranes have ruptured
- Depending on style C-section or suture removed
Corticostroids in Preterm Labour
- All pregnant women between 24 and 34 weeks gestation, who are at risk of preterm delivery within 7 days should be considered candidates for antenatal treatment with a single course of corticosteroids
- A single course of corticosteroids reduces perinatal mortality, respiratory distress syndrom (RDS) and intraventricular hemorrhage
-
Batamethasone 12mg IM q24h x 2 doses or Dexamethasone 6mg IM q12h x4 doses
- Most effective if given at least 24 hours before delivery
Magnesium Sulfate (MgSO4) for Fetal Neuroprotection
- New evidence that antenatal MgSO4 is neuro protective
- Whem women present with imminent preterm birth at <31 +6 weeks
- Active labor with >4cm dilation with or without PROM
- Planned preterm borth for fetal or maternal indications
- 4g IV loading dose over 30 mins then 1g/hour maintenance until delivery
- NOT to stop the labour BUT for fetal neuro protection
Bleeding in Pregnancy
- Spontaneous abrotion (miscarriage)
- Ectopic pregnancy
- Gestational trophoblastic disease
- Placenta previa
- Abruption placentae
- Uterine rupture
Bleeding in the First and Second Trimester
- Abortion: Expulsion of fetus before 20 weeks gestation OR Expulsion of fetus less than 500g
- Spontaneous: occur naturally
- Therapeutic/ Induced: medical or surgical means
Threatened Abortion
- Have some bleeding but the cervix is not dilated and the placenta is still attached to the uterine wall
- Can resolve on its own with rest and monitoring.
Emanate Abortion
- Placenta has started to separate and cervix is dilated and there is more bleeding
- Can progress to an incomplete abortion, fetus or embryo has passed out of the uterus but the placenta remain OR complete where all the products of contraception has passed
Missed Abortion
- Situation where the non-viable embryo starts in the uterus for at least 6 weeks
Habitual Abortion
Someone who has a history of three or more spontaneous abortions
Spontaneous Abrotion Care
- Tretment can range from no treatment to hospitalization
-
If minimal bleeding
- Bed rest and abstinence from sex
-
If persistent/ heavy bleeding, fever = Emergent situation
- Cytotec (misoprostol)/RU 486/Cervidil
- Abortion pill; 2 pill therapy
- +/- WinRho
- Need to know moms blood type
- If mom is negative- will give WinRho
- IV therapy or blood transfusions
- •Surgical Dilatation and curettage (D&C) or suction evacuation (D&E)
- Cervix dilated and the curettage goes into the uterus and scraps out any remain products of conception
- Upside: Faster, reduce the duration of bleeding BUT most of the time is usually not the treatment of choice
Ecotopic Pregnancy
- Implantation of fertilized ovum outside uterus
- Can be any where outside the uterus
- Most often outside the fallopian tubes
- Is a mdical emergency
- Initially symptomsof preganncy )positive hCG)
- As the embryo grows can lead to a rupture
- Happen within 4 to 8 weeks
- Rupture and bleeding into the abdominal cavity
- Rsults in sharp unilateral pain and decreased BP, syncope
- Referred shoulder pain, lower abdominal pain
- Vaginal bleeding
- Hypovolemic shock
- Emergent situation
Gestational Trophoblastic Disease
- RARE (<1/1000) pathologic tumor of childbearing age women
- Abnormal development of the placenta
- Trophoblastic cells that obliterate the pregnancy
- Hydatidifirm mole (benign)
- Can develop into choricocarcinoma (rare)
- Classic signs of pregnancy ++ eacerbated
- Uterine enlergment greater than gestational age, vaginal
- Bleeding, passage of clots
- Hyperemesis gravidarum
- Development of pre-exlampsia prior to 24 weeks
Antepartum Hemorrhage
- Vaginal bleeding >20 weeks- delivery
- Not appropriate to do a vaginal exam if there is bleeding0 can potentially rupture the placenta
- Two main causes- placental (can also be uterine, cervical)
- Placenta previa
- Abruptio placentae
- A change in fetal status might be the first indication of maternal compensation secondary to hemorrhage
Placenta Previa
- When the placenta covers the cervical os
- Location of implantation of the placenta
- Total/ complete
- Cannot deliver vaginaly
- Parial
- High risk
- Marginal
- Low-lying placenta
- Has to do with how the uterus is growing and ends up moving away from the cervical os
- Total/ complete
Detection of Placenta Previ
- Routine ultrasound
- Ultrasound at time of presentation with bleeding
- Must be monitored frquently
- 80+% migrate during pragnancy (low-lying placenta)
- Goal is to get to 36 to 37 weeks gestation
Risk Factors for Placenta Previa
- Previous placenta previa
- Uterine abnormalities/ endometrial scarring
- Impeded endometrial vascularization
- Large placental mass
- Unknow
Abruption Placentae
- Premature separation of normally implanted placenta from uterinwall
- Total/ Complete (Emergency)
- Maternal hemorrhage
- Fetal death
- Parial
- Fetus can tolerate up to 30 to 50% abruption
- Mom can lose 1L to 2L of blood before she become shemodynamic unstable
- Total/ Complete (Emergency)
Risk Factors for Abruption Placentae
- Previous abrutpion
- Hypertension in pregnancy
- Blunt abdominal trauma
- MVA, IPV, Falls
- Overdistended uterus
- PPROM <34 weeks gestation
- Previous C-section, especially short interpregnancy interval
- Cocain or crack use, alcohol use
- Smoking, especually >1 pack/day
- Extremely short umbilical cord
- Uterine abnormalites- fibroids at implantation site
- Advanced maternal age (>35) pr parity
Implications of Abruption Placentae: Maternal
- Intrapearum and postpartum hemorrhage
- DIC
- Hemorrhagic shock
Implications of Abruption Placentae: Fetal-Neonatal
- Sequelae of prematurity
- Hypoxia
- Anemia
- brain damage
- Fetal demise
Immediate Care for Abruption Placentae Bleed
- When able, a complete history and physical
- Assess maternal cardiovasc ular status frquently include O2 saturation, output Including vaginal bleeding) LOC
- If bleeding heavily- doing vitals every 5 minutes
- Fluid resuscitation if active bleeding or unstable
- Want 1 or 2 large bore IVs
- Monitor fetus and uterine activity electronically
Nursing Care
- Prepare equipment for examination
- Oxygen per mask/ prongs
- Obtain an order to type and cross match for blood
- Assess coping mechanisms of woman and family, support
- Review and evaluated diagnostic tests
- Hgb, PT/PTT, type and cross mathc, watch for DIC
- Prepare for cesarean, as needed
- Neonatal resucitation team, as needed
- Pain relief, as needed
- Bed rest, may need hospitalization
- Avoid sexual activity
- No vaginal exames
- Objectively and subjectively assess
- Blood loss, pain, uterine contractilty, coping
Vasa Previa
- Occurs with velamatous insertion of cord
- Vessels of umbilical cord divide some distance from placenta in placental membranes
- Torn vessel leads to fetal hemorrhage
- Leads to non-reassuring fetal status and high mortality
Uterine Rupture
Spontaneous rupture or rupture of previous scar
Risk Factors for Uterine Rupture
- Previous uterine srugery, inclduing cesarean
- Short inter delivery interval (less than 18 months)
- Grand multiparity
- Trauma
- Intrauterine manipulation
- Midforceps rotation of fetus
Presentation of Uterine Rupture
- May initially by asymptomatic
- Abdominal pain not relieved by analgesia / anesthesia
- Uterine activity may or may not stop, dilation will cease
- Vomiting, syncope, vaginal bleeding, maternal/ fetal tachycardia, abnormal FHR, pallow (signs of shock)
- Shape of abdomen changes
- Fetal parts palpable through abdominal wall
- Suspect uterine rupture if dramatic sharp, tearing pain, tense,a cute abdomen, shoulder pain
- Complete cardiovascualr collapse