LEC 46 Water Soluble Vitamins II & Minerals

Question 1

What vitamin is found within Coenzyme A?

Answer 1

Pantothenic Acid (B5)

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Question 2

What are the nutritional and clinical aspects of pantothenic acid?

Answer 2

• widely distributed
• recognized deficiency is rare
• associated with burning foot syndrome

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Question 2

Which B vitamin is biotin?

Answer 2

B7

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Question 3

What is the mechanism of biotin-dependent carboxylase?

Ex: Pyruvate carboxylase

Answer 3

biotin accepts a carboxy residue (CO2)

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Question 4

If someone were to hypothetically eat a lot of raw eggs (egg whites), they could become deficient in what vitamin?

Why does this occur?

Answer 4

Biotin

Avidin in egg whites binds biotin

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Question 5

Purine synthesis requires which vitamin?

Answer 5

Folic Acid (B9)

Question 6

How do you test for folic acid deficiency?

Answer 6

Formiminoglutamic Acid (FIGLU) test

Without folate, FIGLU excretion in the urine INCREASES

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Question 7

What enzyme reduces Fe3+ to Fe2+?

Where is this enzyme located? Why is it necesary?

Answer 7

Ferrireductase
must be reduced in order to be transported across the enterocyte cell membrane by the divalent metal transporter (DMT-1)

Question 8

Ferrous iron is which ion?

Answer 8

Fe2+

Question 9

Ferric iron is which ion?

Answer 9

Fe3+

Question 10

What vitamin is a coenzyme for the ferrireductase rxn?

Answer 10

Vitamin C