Lec 4 Flashcards

1
Q

Can drugs migrate to site of action?

A

Yes

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2
Q

What does absorption, distribution, metabolism and excretion of a drug all involve?

A

Transport across cell membranes

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2
Q

What does absorption, distribution, metabolism and excretion of a drug all involve?

A

Transport across cell membranes

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3
Q

What factors affect drug characteristics of Absorption, distribution, metabolism, and excretion? (4)

A
  • Molecular size
  • Degree of ionization
  • Lipid solubility of ionized and non ionized forms
  • Affinity and binding to serum and tissue protein
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