Lec 2 - The Heart Flashcards
list the differences between excitation of vertebrate striated muscle and cardiac muscle
initial cause of depolarisation, time course of AP, propagation of AP along sarcolemma, cellular origins of Ca2+
voltage gated ca2+ channels open to cause an increase in cytoplasmic Ca2+ only in
cardiac cells
what is special about the refractory period in cardiac muscle
it is a prolonged effective refractory period to allow full emptying of the heart
what does myogenic mean
that it is beginning in the muscle, spontaneous
list two properties of pacemaker cells
they depolarise fastest and have an unstable resting potential
neurogenic means
beginning in the nerve
what are neurogenic neurons excited by
neurotransmitters from motor nerves
what two types of innervation sites can skeletal muscles have
multiple (tonic) or single (twitch)
muscle contraction depends upon
intracellular calcium
skeletal muscle sarcoplasmic reticulum can be described as being
highly developed
cardiac myocyte sarcoplasmic reticulum t tubules are not so well developed because
the signal travels through gap junctions