Lec 2 Flashcards
5 main cytologic classifications of lesions
Cystic Hemorrhagic Inflammatory Neoplastic Mixed cells
What are follicular cysts composed of? When might it become inflamed?
Keritanized cell, amorphous materials and cholesterol crystal.
Can become inflamed when rupture
Two types of pigment seen with hemorrhage
Hemosiderin and hematoidin
Primary considerations for different types of inflammmation….
- Neutrophilia
Neutrophilia = infection, sterile inflammation, immune mediated, neoplasia
Primary considerations for different types of inflammmation….
- Pyogranulomtous
Pyogranulomatous = FB, injection rxn, panniculitis, furunculosis, fungal/Protozoa, some bacteria (nocardia, mycobacterium, actinomyces)
Primary considerations for different types of inflammmation….
- Eosinophilic
Eosinophilic = allergy/hypersensitivity, fungal/parasitic, Eosinphilic Granuloma Complex, +/- neoplasia
Primary considerations for different types of inflammmation….
- Lymphoplasmacytic
Lymphoplasmacytic = antigen/immune stimulation, early viral, chronic inflammation, regressing histiocytoma, neoplasia
4 different types of inflammation
Neutrophilic
Pyogranulomatous
Eosinophilic
Lymphoplasmacytic
what cell type and part of the cell can you see “degenerative” changes”
Seen in nucleus of neutrophils
(karyolyysis, karyorrhexis, pyknosis)
What are the implications of degenerative changes to neutrophils? Could it be artifact?
Indicate cell death in tissues
can be artifact if blood has sat for long time
What four categories of tissue of origin for neoplastic lesions
Epeithial: exfoliate clumps/sheets, rounded cytoplasm
Mesenchymal: exfoliate individually, wispy cytoplasm
Round cell: exfoliate individually
Neruoendocrine: exfoliate well, tend to be ruptured with indistinct cell border
