Lec 16 Flashcards
proparacaine and tetracaine are examples of?
ophthalmic anesthetics
gentamicin and tobramycin are examples of?
ophthalmic antibiotics
natamycin is an example of?
what does it treat?
ophthalmic antifungal
fungal keratitis
Fluorometholone and Prednisolone are examples of?
ophthalmic anti-inflamm
Trifluridine and Ganciclovir are examples of?
what do they treat?
ophthalmic antivirals
herpes
Zinc sulfate ophthalmic solution is an example of?
what does it treat?
ophthalmic astringent
conjunctivitis
Pilocarpine ophthalmic solution is an example of?
what does it treat?
a miotic
glaucoma
what do ophthalmic miotics do?
lower intraocular pressure or constrict pupil
Timolol ophthalmic solution is an example of?
what does it treat?
Beta-blocker
glaucoma
what do ophthalmic mydriatics do?
dilate pupil for use of examinations
Atropine sulfate is an example of?
ophthalmic mydriatic
what do ophthalmic cycloplegics do?
paralyze eye muscles for examinations/surgery
Homatropine is an example of?
ophthalmic cycloplegic
T/F topical route is used to treat diseases that effect the anterior segment of the eye (e.g. conjunctivitis, glaucoma, and keratitis)
true
T/F The optimal volume to administer, based on eye capacity, is 7 to 10 microL.
True
T/F Ophthalmic preservatives are effective agents at maintaining sterility in their products
False, they should not be the sole means of sterilizing a product
what do detergent preservatives do?
cause bacterial cell death by interrupting the lipid component of cell membranes
Benzalkonium chloride (BAK) is an example of a?
detergent preservative
what do oxidative preservatives do?
cause bacterial cell death by altering the DNA
sodium perborate is an example of a?
oxidative preservative
what do ionic-buffering preservatives do?
cause bacterial cell death by altering the DNA,
SofZia is an example of a?
ionic-buffering preservative
T/F purified water is the main vehicle used for ocular products
true
ophthalmic solutions should be formulated at a pH equivalent to the tear fluid v
7.4
T/F Many drugs are insoluble in water at pH 7.4
True
T/F Boric acid is a common buffer for eye drops
true
T/F Boric acid has antiviral properties
false, it has antibacterial properties
what are eye lotions used for?
assist in cleaning the eye
what’s the main advantage of using a gel over a liquid?
increased contact time and drug absorption
