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Pharmaceutics I > Lec 16 > Flashcards

Lec 16 Flashcards

1
Q

proparacaine and tetracaine are examples of?

A

ophthalmic anesthetics

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2
Q

gentamicin and tobramycin are examples of?

A

ophthalmic antibiotics

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3
Q

natamycin is an example of?

what does it treat?

A

ophthalmic antifungal

fungal keratitis

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4
Q

Fluorometholone and Prednisolone are examples of?

A

ophthalmic anti-inflamm

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5
Q

Trifluridine and Ganciclovir are examples of?

what do they treat?

A

ophthalmic antivirals

herpes

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6
Q

Zinc sulfate ophthalmic solution is an example of?

what does it treat?

A

ophthalmic astringent

conjunctivitis

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7
Q

Pilocarpine ophthalmic solution is an example of?

what does it treat?

A

a miotic

glaucoma

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8
Q

what do ophthalmic miotics do?

A

lower intraocular pressure or constrict pupil

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9
Q

Timolol ophthalmic solution is an example of?

what does it treat?

A

Beta-blocker

glaucoma

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10
Q

what do ophthalmic mydriatics do?

A

dilate pupil for use of examinations

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11
Q

Atropine sulfate is an example of?

A

ophthalmic mydriatic

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12
Q

what do ophthalmic cycloplegics do?

A

paralyze eye muscles for examinations/surgery

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13
Q

Homatropine is an example of?

A

ophthalmic cycloplegic

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14
Q 
T/F topical route is used to treat diseases that effect the anterior segment of 
the eye (e.g. conjunctivitis, glaucoma, and keratitis)
A

true

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15
Q

T/F The optimal volume to administer, based on eye capacity, is 7 to 10 microL.

A

True

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16
Q

T/F Ophthalmic preservatives are effective agents at maintaining sterility in their products

A

False, they should not be the sole means of sterilizing a product

17
Q

what do detergent preservatives do?

A

cause bacterial cell death by interrupting the lipid component of cell membranes

18
Q

Benzalkonium chloride (BAK) is an example of a?

A

detergent preservative

19
Q

what do oxidative preservatives do?

A

cause bacterial cell death by altering the DNA

20
Q

sodium perborate is an example of a?

A

oxidative preservative

21
Q

what do ionic-buffering preservatives do?

A

cause bacterial cell death by altering the DNA,

22
Q

SofZia is an example of a?

A

ionic-buffering preservative

23
Q

T/F purified water is the main vehicle used for ocular products

A

true

24
Q

ophthalmic solutions should be formulated at a pH equivalent to the tear fluid v

A

7.4

25
Q

T/F Many drugs are insoluble in water at pH 7.4

A

True

26
Q

T/F Boric acid is a common buffer for eye drops

A

true

27
Q

T/F Boric acid has antiviral properties

A

false, it has antibacterial properties

28
Q

what are eye lotions used for?

A

assist in cleaning the eye

29
Q

what’s the main advantage of using a gel over a liquid?

A

increased contact time and drug absorption

Pharmaceutics I (6 decks)

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