LEC 15-16 Flashcards
What is the core structure of ATP?
Ribose sugar, Adenine nitrogenous base, and a phosphate group
Which phosphate has the lowest energy (G) state?
AMP (Adenosine monophosphate)
Which phosphate has the highest energy (G) state?
ATP (Adenosine triphosphate)
Which phosphate has the middle energy (G) state?
ADP (Adenosine diphosphate)
Where is the energy contained in an ATP molucule?
The bonds between the phosphate groups (i.e. the bond between AMP and ADP and the bond between ADP and ATP)
Is ATP hydrolysis an endergonic or exergonic reaction?
Exergonic
What are the reactants of ATP hydrolysis?
ATP and water
What are the products of ATP hydrolysis?
ADP and Pi (inorganic phosphate)
How much energy is released during ATP hydrolysis?
Change in G = -7.3 Kcal/mol
What the reactants in the synthesis of glutamine?
Glutamate and NH4
What the products of glutamine synthesis?
Glutamine
Is the synthesis of glutamine endergonic or exergonic? And how much energy does it absorb or release?
Endergonic and absorbs 3.4 Kcal/mol
If you were to couple the hydrolysis of ATP with the synthesis of glutamine, what would the reactants be?
ATP, water, glutamate, NH4
If you were to couple the hydrolysis of ATP with the synthesis of glutamine, what would the products be?
ADP, Pi, and glutamine
If you were to couple the hydrolysis of ATP with the synthesis of glutamine, what would the change of energy be?
-3.9 Kcal/mol (net exergonic)
What is the kinetics of a reaction?
Refers to the “rate” at which a reaction occurs
What does the thermodynamics of a reaction refer to?
Refers to whether free energy was released or absorbed
What does activation energy influence?
It affects the rate of a reaction
What is activation energy?
The amount of G (free energy) required to start a chemical reaction
What is the relationship between activation energy and rate of reaction?
Indirectly related; the higher the activation energy, the lower the rate of reaction
What are the two components of activation energy?
Collision energy of reactants and the orientation of reactants during collisions
What do catalysts do?
Lower activation energy and increase the rate of reaction
What are enzymes?
Biological catalysts